Attitudes to prenatal diagnosis and termination of pregnancy for fetal abnormalities in Saudi couples: a single center experience

Background: Prenatal diagnosis (PND) is an effective method for early detection of genetics and hereditary diseases during pregnancy in order to help the couple to take the proper decision regarding affected fetus. The current study aimed at assessing the attitude of Saudi couple regarding prenatal...

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Main Authors: Maha Alshalan, Majid Alfadhel
Format: Article
Language:English
Published: Discover STM Publishing Ltd 2019-12-01
Series:Journal of Biochemical and Clinical Genetics
Subjects:
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=74325
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author Maha Alshalan
Majid Alfadhel
author_facet Maha Alshalan
Majid Alfadhel
author_sort Maha Alshalan
collection DOAJ
description Background: Prenatal diagnosis (PND) is an effective method for early detection of genetics and hereditary diseases during pregnancy in order to help the couple to take the proper decision regarding affected fetus. The current study aimed at assessing the attitude of Saudi couple regarding prenatal diagnosis and termination of pregnancy (TOP) for fetal abnormalities. Methodology: A descriptive cross-sectional was carried out; 100 couples attended Genetic Clinics in King Abdullah Specialized Childrens Hospital in Riyadh, who were interviewed using an questionnaire consisting of four parts covering socio-demographic data of participants, family & obstetric history, knowledge, and attitude of couples regarding PND and TOP. Descriptive statistics and chi-square tests were used for data analysis. Results: The results of the study showed that the mean age of fathers were 38.8± 8.1 years, while the mean age of mothers were 33.9 ± 6.9 and most of the couples (93%) lived in the urban area. Among them, 47% of couples had a positive family history of genetic diseases; 16% of mothers performed PND in their previous pregnancies. Among them, 62% and 76% of fathers and mothers, respectively, had satisfactory knowledge about PND and TOP with a statistically significant difference between them. Conclusion: A comprehensive genetic counselling service offered to the couples may influence the decision on TOP. The awareness about PND and TOP is crucial to obtain good understanding and positive future strategies. [JBCGenetics 2019; 2(2.000): 99-106]
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spelling doaj.art-e268d4f570ba4a0dbe6abfe485bec7712023-05-30T11:45:05ZengDiscover STM Publishing LtdJournal of Biochemical and Clinical Genetics1658-807X2019-12-01229910610.24911/JBCGenetics/183-157415271974325Attitudes to prenatal diagnosis and termination of pregnancy for fetal abnormalities in Saudi couples: a single center experienceMaha Alshalan0Majid Alfadhel1Division of Genetics, Department of Pediatrics, King Abdullah specialized Childrens Hospital, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs (MNGHA), Riyadh, Saudi Arabia Division of Genetics, Department of Pediatrics, King Abdullah specialized Childrens Hospital, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs (MNGHA), Riyadh, Saudi Arabia, Medical Genomics Research Department, King Abdullah International Medical Research Center (KAIMRC), Ministry of National Guard-Health Affairs (MNGHA), Riyadh, Saudi Arabia, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs (MNGHA), Riyadh, Saudi ArabiaBackground: Prenatal diagnosis (PND) is an effective method for early detection of genetics and hereditary diseases during pregnancy in order to help the couple to take the proper decision regarding affected fetus. The current study aimed at assessing the attitude of Saudi couple regarding prenatal diagnosis and termination of pregnancy (TOP) for fetal abnormalities. Methodology: A descriptive cross-sectional was carried out; 100 couples attended Genetic Clinics in King Abdullah Specialized Childrens Hospital in Riyadh, who were interviewed using an questionnaire consisting of four parts covering socio-demographic data of participants, family & obstetric history, knowledge, and attitude of couples regarding PND and TOP. Descriptive statistics and chi-square tests were used for data analysis. Results: The results of the study showed that the mean age of fathers were 38.8± 8.1 years, while the mean age of mothers were 33.9 ± 6.9 and most of the couples (93%) lived in the urban area. Among them, 47% of couples had a positive family history of genetic diseases; 16% of mothers performed PND in their previous pregnancies. Among them, 62% and 76% of fathers and mothers, respectively, had satisfactory knowledge about PND and TOP with a statistically significant difference between them. Conclusion: A comprehensive genetic counselling service offered to the couples may influence the decision on TOP. The awareness about PND and TOP is crucial to obtain good understanding and positive future strategies. [JBCGenetics 2019; 2(2.000): 99-106]http://www.ejmanager.com/fulltextpdf.php?mno=74325prenatal diagnosistermination of pregnancyfetal abnormalitiessaudi couplesattitude
spellingShingle Maha Alshalan
Majid Alfadhel
Attitudes to prenatal diagnosis and termination of pregnancy for fetal abnormalities in Saudi couples: a single center experience
Journal of Biochemical and Clinical Genetics
prenatal diagnosis
termination of pregnancy
fetal abnormalities
saudi couples
attitude
title Attitudes to prenatal diagnosis and termination of pregnancy for fetal abnormalities in Saudi couples: a single center experience
title_full Attitudes to prenatal diagnosis and termination of pregnancy for fetal abnormalities in Saudi couples: a single center experience
title_fullStr Attitudes to prenatal diagnosis and termination of pregnancy for fetal abnormalities in Saudi couples: a single center experience
title_full_unstemmed Attitudes to prenatal diagnosis and termination of pregnancy for fetal abnormalities in Saudi couples: a single center experience
title_short Attitudes to prenatal diagnosis and termination of pregnancy for fetal abnormalities in Saudi couples: a single center experience
title_sort attitudes to prenatal diagnosis and termination of pregnancy for fetal abnormalities in saudi couples a single center experience
topic prenatal diagnosis
termination of pregnancy
fetal abnormalities
saudi couples
attitude
url http://www.ejmanager.com/fulltextpdf.php?mno=74325
work_keys_str_mv AT mahaalshalan attitudestoprenataldiagnosisandterminationofpregnancyforfetalabnormalitiesinsaudicouplesasinglecenterexperience
AT majidalfadhel attitudestoprenataldiagnosisandterminationofpregnancyforfetalabnormalitiesinsaudicouplesasinglecenterexperience