Blockade of Store-Operated Calcium Entry Reduces IL-17/TNF Cytokine-Induced Inflammatory Response in Human Myoblasts

Blockade of Store-Operated Calcium Entry Reduces IL-17/TNF Cytokine-Induced Inflammatory Response in Human Myoblasts

Muscle inflammation as in idiopathic inflammatory myopathies (IIM) leads to muscle weakness, mononuclear cell infiltration, and myofiber dysfunction affecting calcium channels. The effects of interleukin-17A (IL-17) and tumor necrosis factor-α (TNFα) on inflammation and calcium changes were investig...

Full description

Bibliographic Details
Main Authors: Audrey Beringer, Yves Gouriou, Fabien Lavocat, Michel Ovize, Pierre Miossec
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
inflammatory myopathies
interleukin-17
tumor necrosis factor-α
store-operated calcium entry
myoblasts
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03170/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.03170/full

Similar Items