Generation of Dip2a homozygous knockout murine ES cell line IBMSe001-A-1 via CRISPR/Cas9 technology

Generation of Dip2a homozygous knockout murine ES cell line IBMSe001-A-1 via CRISPR/Cas9 technology

DIP2A mutation is associated with abnormal brain development and diseases including dyslexia, autism and Alzheimer's disease. However, the role and the involved mechanisms remain unknown. To study the biological function of DIP2A during mESCs neural differentiation in early neural development,...

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Bibliografiske detaljer
Main Authors: Mingze Yao, Qian Yang, Mengqiao Lian, Pengfei Su, Xiaogang Cui, Tinglin Ren, Xiedong Wang, Changxin Wu, Yaowu Zheng
Format: Article
Sprog:English
Udgivet: Elsevier 2020-05-01
Serier:Stem Cell Research
Online adgang:http://www.sciencedirect.com/science/article/pii/S1873506120300829

Internet

http://www.sciencedirect.com/science/article/pii/S1873506120300829

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