Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance

Gastric cancer is one of the most common cancers worldwide. The amount of cell-free DNA (cfDNA) in the blood of patients with gastric cancer was found to be higher than that of healthy controls (69.1 ng/μL vs. 34.8 ng/μL). Patients with cfDNA ≤ 50 ng/μL were found to have an increased overall surviv...

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Bibliographic Details
Main Authors: Karamitrousis E., Balgkouranidou I., Xenidis N., Amarantidis K., Biziota E., Koukaki T., Kakolyris S.
Format: Article
Language:English
Published: Sciendo 2022-05-01
Series:Forum of Clinical Oncology
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Online Access:https://doi.org/10.2478/fco-2021-0010
Description
Summary:Gastric cancer is one of the most common cancers worldwide. The amount of cell-free DNA (cfDNA) in the blood of patients with gastric cancer was found to be higher than that of healthy controls (69.1 ng/μL vs. 34.8 ng/μL). Patients with cfDNA ≤ 50 ng/μL were found to have an increased overall survival (OS) and progression free survival (PFS) than in patients with cfDNA > 50 ng/μL.
ISSN:1792-362X