Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance

Gastric cancer is one of the most common cancers worldwide. The amount of cell-free DNA (cfDNA) in the blood of patients with gastric cancer was found to be higher than that of healthy controls (69.1 ng/μL vs. 34.8 ng/μL). Patients with cfDNA ≤ 50 ng/μL were found to have an increased overall surviv...

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Main Authors: Karamitrousis E., Balgkouranidou I., Xenidis N., Amarantidis K., Biziota E., Koukaki T., Kakolyris S.
Format: Article
Language:English
Published: Sciendo 2022-05-01
Series:Forum of Clinical Oncology
Subjects:
Online Access:https://doi.org/10.2478/fco-2021-0010
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author Karamitrousis E.
Balgkouranidou I.
Xenidis N.
Amarantidis K.
Biziota E.
Koukaki T.
Kakolyris S.
author_facet Karamitrousis E.
Balgkouranidou I.
Xenidis N.
Amarantidis K.
Biziota E.
Koukaki T.
Kakolyris S.
author_sort Karamitrousis E.
collection DOAJ
description Gastric cancer is one of the most common cancers worldwide. The amount of cell-free DNA (cfDNA) in the blood of patients with gastric cancer was found to be higher than that of healthy controls (69.1 ng/μL vs. 34.8 ng/μL). Patients with cfDNA ≤ 50 ng/μL were found to have an increased overall survival (OS) and progression free survival (PFS) than in patients with cfDNA > 50 ng/μL.
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spelling doaj.art-e26bb440ad9b4e38bc8a03d923622f302022-12-22T04:16:42ZengSciendoForum of Clinical Oncology1792-362X2022-05-01123727610.2478/fco-2021-0010Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significanceKaramitrousis E.0Balgkouranidou I.1Xenidis N.2Amarantidis K.3Biziota E.4Koukaki T.5Kakolyris S.6University Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, GreeceUniversity Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, GreeceUniversity Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, GreeceUniversity Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, GreeceUniversity Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, GreeceUniversity Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, GreeceUniversity Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, GreeceGastric cancer is one of the most common cancers worldwide. The amount of cell-free DNA (cfDNA) in the blood of patients with gastric cancer was found to be higher than that of healthy controls (69.1 ng/μL vs. 34.8 ng/μL). Patients with cfDNA ≤ 50 ng/μL were found to have an increased overall survival (OS) and progression free survival (PFS) than in patients with cfDNA > 50 ng/μL.https://doi.org/10.2478/fco-2021-0010cell-free dnagastric cancerprognosis
spellingShingle Karamitrousis E.
Balgkouranidou I.
Xenidis N.
Amarantidis K.
Biziota E.
Koukaki T.
Kakolyris S.
Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance
Forum of Clinical Oncology
cell-free dna
gastric cancer
prognosis
title Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance
title_full Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance
title_fullStr Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance
title_full_unstemmed Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance
title_short Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance
title_sort concentration of circulating tumour dna in patients with metastatic gastric cancer and its prognostic significance
topic cell-free dna
gastric cancer
prognosis
url https://doi.org/10.2478/fco-2021-0010
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