Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance
Gastric cancer is one of the most common cancers worldwide. The amount of cell-free DNA (cfDNA) in the blood of patients with gastric cancer was found to be higher than that of healthy controls (69.1 ng/μL vs. 34.8 ng/μL). Patients with cfDNA ≤ 50 ng/μL were found to have an increased overall surviv...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
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Sciendo
2022-05-01
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Series: | Forum of Clinical Oncology |
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Online Access: | https://doi.org/10.2478/fco-2021-0010 |
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author | Karamitrousis E. Balgkouranidou I. Xenidis N. Amarantidis K. Biziota E. Koukaki T. Kakolyris S. |
author_facet | Karamitrousis E. Balgkouranidou I. Xenidis N. Amarantidis K. Biziota E. Koukaki T. Kakolyris S. |
author_sort | Karamitrousis E. |
collection | DOAJ |
description | Gastric cancer is one of the most common cancers worldwide. The amount of cell-free DNA (cfDNA) in the blood of patients with gastric cancer was found to be higher than that of healthy controls (69.1 ng/μL vs. 34.8 ng/μL). Patients with cfDNA ≤ 50 ng/μL were found to have an increased overall survival (OS) and progression free survival (PFS) than in patients with cfDNA > 50 ng/μL. |
first_indexed | 2024-04-11T15:09:57Z |
format | Article |
id | doaj.art-e26bb440ad9b4e38bc8a03d923622f30 |
institution | Directory Open Access Journal |
issn | 1792-362X |
language | English |
last_indexed | 2024-04-11T15:09:57Z |
publishDate | 2022-05-01 |
publisher | Sciendo |
record_format | Article |
series | Forum of Clinical Oncology |
spelling | doaj.art-e26bb440ad9b4e38bc8a03d923622f302022-12-22T04:16:42ZengSciendoForum of Clinical Oncology1792-362X2022-05-01123727610.2478/fco-2021-0010Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significanceKaramitrousis E.0Balgkouranidou I.1Xenidis N.2Amarantidis K.3Biziota E.4Koukaki T.5Kakolyris S.6University Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, GreeceUniversity Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, GreeceUniversity Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, GreeceUniversity Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, GreeceUniversity Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, GreeceUniversity Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, GreeceUniversity Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, GreeceGastric cancer is one of the most common cancers worldwide. The amount of cell-free DNA (cfDNA) in the blood of patients with gastric cancer was found to be higher than that of healthy controls (69.1 ng/μL vs. 34.8 ng/μL). Patients with cfDNA ≤ 50 ng/μL were found to have an increased overall survival (OS) and progression free survival (PFS) than in patients with cfDNA > 50 ng/μL.https://doi.org/10.2478/fco-2021-0010cell-free dnagastric cancerprognosis |
spellingShingle | Karamitrousis E. Balgkouranidou I. Xenidis N. Amarantidis K. Biziota E. Koukaki T. Kakolyris S. Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance Forum of Clinical Oncology cell-free dna gastric cancer prognosis |
title | Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance |
title_full | Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance |
title_fullStr | Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance |
title_full_unstemmed | Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance |
title_short | Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance |
title_sort | concentration of circulating tumour dna in patients with metastatic gastric cancer and its prognostic significance |
topic | cell-free dna gastric cancer prognosis |
url | https://doi.org/10.2478/fco-2021-0010 |
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