Switch to low-fat diet improves outcome of acute lymphoblastic leukemia in obese mice

Switch to low-fat diet improves outcome of acute lymphoblastic leukemia in obese mice

Abstract Background It is becoming increasingly recognized that weight and nutritional status can impact cancer survival. We have previously shown that obese mice with syngeneic acute lymphoblastic leukemia (ALL) have poorer response to chemotherapy treatment than control mice. We therefore investig...

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Bibliographic Details
Main Authors: Jonathan Tucci, Waseem Alhushki, Ting Chen, Xia Sheng, Yong-Mi Kim, Steven D. Mittelman
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Cancer & Metabolism
Subjects:
Obesity
Adipose tissue
Dietary intervention
Chemotherapy
Caloric restriction
Online Access:http://link.springer.com/article/10.1186/s40170-018-0189-0

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