Correlation of the disease-specific Canadian Cardiovascular Society (CCS) classification and health-related quality of life (15D) in coronary artery disease patients.

<h4>Background</h4>Generic health-related quality of life (HRQoL) and disease-specific instruments measure HRQoL from different aspects, although generic instruments often contain dimensions that reflect common symptoms. We evaluated how the change in 15D HRQoL and Canadian Cardiovascula...

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Main Authors: Jarno Kotajärvi, Anna-Maija Tolppanen, Juha Hartikainen, Heikki Miettinen, Marketta Viljakainen, Janne Martikainen, Risto P Roine, Piia Lavikainen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0266101
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author Jarno Kotajärvi
Anna-Maija Tolppanen
Juha Hartikainen
Heikki Miettinen
Marketta Viljakainen
Janne Martikainen
Risto P Roine
Piia Lavikainen
author_facet Jarno Kotajärvi
Anna-Maija Tolppanen
Juha Hartikainen
Heikki Miettinen
Marketta Viljakainen
Janne Martikainen
Risto P Roine
Piia Lavikainen
author_sort Jarno Kotajärvi
collection DOAJ
description <h4>Background</h4>Generic health-related quality of life (HRQoL) and disease-specific instruments measure HRQoL from different aspects, although generic instruments often contain dimensions that reflect common symptoms. We evaluated how the change in 15D HRQoL and Canadian Cardiovascular Society (CCS) grading of angina severity correlate among coronary artery disease patients during 12-month follow-up.<h4>Methods</h4>Altogether 1 271 patients scheduled for coronary angiography between June 2015 and February 2017 returned the 15D HRQoL and CCS questionnaires before angiography and after one-year follow-up as a part of routine clinical practice. Spearman correlations between one-year changes in the CCS and the 15D and its dimensions were evaluated. Changes in 15D were classified into 5 categories based on the reported minimal important difference (MID) for the instrument.<h4>Results</h4>Change in the CCS grade correlated moderately with the MID-based change in the 15D (r = 0.33, 95% confidence interval 0.27-0.39). Correlations between these instruments were similar in different age groups, between sexes and treatment modalities. Of the individual 15D dimensions, changes in breathing (r = 0.40) and vitality (r = 0.30) had the strongest correlations with CCS change.<h4>Conclusion</h4>The symptom-based evaluation of the change in the CCS grade may not catch the full benefit or harm of the treatment and vice versa, a generic instrument, such as 15D, likely does not fully capture change in disease-specific symptoms. Thus, generic and disease-specific instruments are complementary and should be used in conjunction.
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spelling doaj.art-e26dc9c6cb9449c8be54c1459869bd9d2022-12-22T02:34:07ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01174e026610110.1371/journal.pone.0266101Correlation of the disease-specific Canadian Cardiovascular Society (CCS) classification and health-related quality of life (15D) in coronary artery disease patients.Jarno KotajärviAnna-Maija TolppanenJuha HartikainenHeikki MiettinenMarketta ViljakainenJanne MartikainenRisto P RoinePiia Lavikainen<h4>Background</h4>Generic health-related quality of life (HRQoL) and disease-specific instruments measure HRQoL from different aspects, although generic instruments often contain dimensions that reflect common symptoms. We evaluated how the change in 15D HRQoL and Canadian Cardiovascular Society (CCS) grading of angina severity correlate among coronary artery disease patients during 12-month follow-up.<h4>Methods</h4>Altogether 1 271 patients scheduled for coronary angiography between June 2015 and February 2017 returned the 15D HRQoL and CCS questionnaires before angiography and after one-year follow-up as a part of routine clinical practice. Spearman correlations between one-year changes in the CCS and the 15D and its dimensions were evaluated. Changes in 15D were classified into 5 categories based on the reported minimal important difference (MID) for the instrument.<h4>Results</h4>Change in the CCS grade correlated moderately with the MID-based change in the 15D (r = 0.33, 95% confidence interval 0.27-0.39). Correlations between these instruments were similar in different age groups, between sexes and treatment modalities. Of the individual 15D dimensions, changes in breathing (r = 0.40) and vitality (r = 0.30) had the strongest correlations with CCS change.<h4>Conclusion</h4>The symptom-based evaluation of the change in the CCS grade may not catch the full benefit or harm of the treatment and vice versa, a generic instrument, such as 15D, likely does not fully capture change in disease-specific symptoms. Thus, generic and disease-specific instruments are complementary and should be used in conjunction.https://doi.org/10.1371/journal.pone.0266101
spellingShingle Jarno Kotajärvi
Anna-Maija Tolppanen
Juha Hartikainen
Heikki Miettinen
Marketta Viljakainen
Janne Martikainen
Risto P Roine
Piia Lavikainen
Correlation of the disease-specific Canadian Cardiovascular Society (CCS) classification and health-related quality of life (15D) in coronary artery disease patients.
PLoS ONE
title Correlation of the disease-specific Canadian Cardiovascular Society (CCS) classification and health-related quality of life (15D) in coronary artery disease patients.
title_full Correlation of the disease-specific Canadian Cardiovascular Society (CCS) classification and health-related quality of life (15D) in coronary artery disease patients.
title_fullStr Correlation of the disease-specific Canadian Cardiovascular Society (CCS) classification and health-related quality of life (15D) in coronary artery disease patients.
title_full_unstemmed Correlation of the disease-specific Canadian Cardiovascular Society (CCS) classification and health-related quality of life (15D) in coronary artery disease patients.
title_short Correlation of the disease-specific Canadian Cardiovascular Society (CCS) classification and health-related quality of life (15D) in coronary artery disease patients.
title_sort correlation of the disease specific canadian cardiovascular society ccs classification and health related quality of life 15d in coronary artery disease patients
url https://doi.org/10.1371/journal.pone.0266101
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