Alcohol and tea consumption are associated with asymptomatic erosive esophagitis in Taiwanese men.
OBJECTIVE:Asymptomatic erosive esophagitis (AEE) is commonly found in men, and might be a risk factor of developing esophageal adenocarcinoma. We aimed to determine if specific dietary habits increase the risk of AEE in asymptomatic Taiwanese men. METHODS:We recruited male adults undergoing upper ga...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5338804?pdf=render |
| _version_ | 1818357512204713984 |
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| author | Chung-Hsin Chang Cheng-Pin Wu Jung-Der Wang Shou-Wu Lee Chi-Sen Chang Hong-Zen Yeh Chung-Wang Ko Han-Chung Lien |
| author_facet | Chung-Hsin Chang Cheng-Pin Wu Jung-Der Wang Shou-Wu Lee Chi-Sen Chang Hong-Zen Yeh Chung-Wang Ko Han-Chung Lien |
| author_sort | Chung-Hsin Chang |
| collection | DOAJ |
| description | OBJECTIVE:Asymptomatic erosive esophagitis (AEE) is commonly found in men, and might be a risk factor of developing esophageal adenocarcinoma. We aimed to determine if specific dietary habits increase the risk of AEE in asymptomatic Taiwanese men. METHODS:We recruited male adults undergoing upper gastrointestinal endoscopy for health check. We excluded subjects with reflux symptoms, or taking anti-reflux medications or drugs that potentially impair lower esophageal sphincter function or cause mucosal injury. The frequency of consuming reflux-provoking diets including alcohol, tea, coffee, tomato/citric juice, chocolate, sweet food, and spicy food was assessed. The erosive esophagitis was diagnosed based on the Los Angeles Classification after endoscopy. Frequent consumption of a specific diet was defined as ≥4 days/week of consuming that diet. RESULTS:A total of 1256 participants were recruited. After excluding 424 ineligible subjects, AEE was identified in 180 (22%) among 832 asymptomatic subjects. The risk of AEE increased with the number of days per week of consuming alcohol or tea: nondrinkers (19%, 17%), occasional drinkers (<1 day/week; 19%, 15%), regular drinkers (1-3 days/week; 26%, 21%), frequent drinkers (4-6 days/week; 32%, 22%), and daily drinkers (42%, 28%), respectively (trend test P < 0.001 for both). Multivariate analysis showed that hiatus hernia (adjusted odds ratio (aOR) 5.0, 95% confidence interval (CI) 2.6-9.6), drinking alcohol ≥4 days/week (aOR 2.3, 95% CI 1.3-4.0), and drinking tea ≥4 days/week (aOR 1.6, 95% CI 1.1-2.3) are independent risk factors of AEE. The risk of AEE was 3.8 times greater for those drinking both alcohol and tea ≥4 days/week than the non-drinkers. CONCLUSIONS:Frequent alcohol and tea consumption increased the risk of AEE in Taiwanese men. |
| first_indexed | 2024-12-13T20:14:17Z |
| format | Article |
| id | doaj.art-e26e55343662497e898b4ace1335b3ac |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-13T20:14:17Z |
| publishDate | 2017-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-e26e55343662497e898b4ace1335b3ac2022-12-21T23:32:51ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01123e017323010.1371/journal.pone.0173230Alcohol and tea consumption are associated with asymptomatic erosive esophagitis in Taiwanese men.Chung-Hsin ChangCheng-Pin WuJung-Der WangShou-Wu LeeChi-Sen ChangHong-Zen YehChung-Wang KoHan-Chung LienOBJECTIVE:Asymptomatic erosive esophagitis (AEE) is commonly found in men, and might be a risk factor of developing esophageal adenocarcinoma. We aimed to determine if specific dietary habits increase the risk of AEE in asymptomatic Taiwanese men. METHODS:We recruited male adults undergoing upper gastrointestinal endoscopy for health check. We excluded subjects with reflux symptoms, or taking anti-reflux medications or drugs that potentially impair lower esophageal sphincter function or cause mucosal injury. The frequency of consuming reflux-provoking diets including alcohol, tea, coffee, tomato/citric juice, chocolate, sweet food, and spicy food was assessed. The erosive esophagitis was diagnosed based on the Los Angeles Classification after endoscopy. Frequent consumption of a specific diet was defined as ≥4 days/week of consuming that diet. RESULTS:A total of 1256 participants were recruited. After excluding 424 ineligible subjects, AEE was identified in 180 (22%) among 832 asymptomatic subjects. The risk of AEE increased with the number of days per week of consuming alcohol or tea: nondrinkers (19%, 17%), occasional drinkers (<1 day/week; 19%, 15%), regular drinkers (1-3 days/week; 26%, 21%), frequent drinkers (4-6 days/week; 32%, 22%), and daily drinkers (42%, 28%), respectively (trend test P < 0.001 for both). Multivariate analysis showed that hiatus hernia (adjusted odds ratio (aOR) 5.0, 95% confidence interval (CI) 2.6-9.6), drinking alcohol ≥4 days/week (aOR 2.3, 95% CI 1.3-4.0), and drinking tea ≥4 days/week (aOR 1.6, 95% CI 1.1-2.3) are independent risk factors of AEE. The risk of AEE was 3.8 times greater for those drinking both alcohol and tea ≥4 days/week than the non-drinkers. CONCLUSIONS:Frequent alcohol and tea consumption increased the risk of AEE in Taiwanese men.http://europepmc.org/articles/PMC5338804?pdf=render |
| spellingShingle | Chung-Hsin Chang Cheng-Pin Wu Jung-Der Wang Shou-Wu Lee Chi-Sen Chang Hong-Zen Yeh Chung-Wang Ko Han-Chung Lien Alcohol and tea consumption are associated with asymptomatic erosive esophagitis in Taiwanese men. PLoS ONE |
| title | Alcohol and tea consumption are associated with asymptomatic erosive esophagitis in Taiwanese men. |
| title_full | Alcohol and tea consumption are associated with asymptomatic erosive esophagitis in Taiwanese men. |
| title_fullStr | Alcohol and tea consumption are associated with asymptomatic erosive esophagitis in Taiwanese men. |
| title_full_unstemmed | Alcohol and tea consumption are associated with asymptomatic erosive esophagitis in Taiwanese men. |
| title_short | Alcohol and tea consumption are associated with asymptomatic erosive esophagitis in Taiwanese men. |
| title_sort | alcohol and tea consumption are associated with asymptomatic erosive esophagitis in taiwanese men |
| url | http://europepmc.org/articles/PMC5338804?pdf=render |
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