Magnaporthe Rab5 homologs show distinct functions in nerve growth factor (NGF)-mediated neurite outgrowth and cell differentiation

Magnaporthe Rab5 homologs show distinct functions in nerve growth factor (NGF)-mediated neurite outgrowth and cell differentiation

Nerve growth factor (NGF) binds to TrkA and forms a NGF/TrkA complex at the cell surface, which is then internalized into signaling endosomes and promotes neuronal survival and neurite outgrowth. The small GTPase Rab5 is reported to localize on the plasma membrane and early endosomes, regulating end...

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Bibliographic Details
Main Authors: Yao-yao QI, Zhi-min LIANG, Jie ZHOU, Zong-hua WANG, Guo-dong LU, Guang-pu LI
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Journal of Integrative Agriculture
Subjects:
NGF
Rab5 GTPase
Magnaporthe oryzae
neurite ourgrowth and cell differentiation
Online Access:http://www.sciencedirect.com/science/article/pii/S2095311914609722

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