Harnessing the cyclization strategy for new drug discovery

The design of new ligands with high affinity and specificity against the targets of interest has been a central focus in drug discovery. As one of the most commonly used methods in drug discovery, the cyclization represents a feasible strategy to identify new lead compounds by increasing structural...

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Bibliographic Details
Main Authors: Kai Tang, Shu Wang, Wenshuo Gao, Yihui Song, Bin Yu
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522004166