Proteomic data show an increase in autoantibodies and alpha-fetoprotein and a decrease in apolipoprotein A-II with time in sera from senescence-accelerated mice

Proteomic data show an increase in autoantibodies and alpha-fetoprotein and a decrease in apolipoprotein A-II with time in sera from senescence-accelerated mice

We evaluated changes in levels by comparing serum proteins in senescence-accelerated mouse-prone 8 (SAMP8) mice at 2, 6, 12, and 15 months of age (SAMP8-2 m, -6 m, -12 m, -15 m) to age-matched SAM-resistant 1 (SAMR1) mice. Mice were sacrificed, and blood was a...

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Bibliographic Details
Main Authors: S.J. Guo, C.H. Qi, W.X. Zhou, Y.X. Zhang, X.M. Zhang, J. Wang, H.X. Wang
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2013-05-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
SAMP8
Serum proteins
2-DE
Mass spectrometry
M-T413
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000500417

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