Hypocretin Levels in Sporadic and Familial Cases of Canine Narcolepsy
Familial and sporadic forms of narcolepsy exist in both humans and canines. Mutations in the hypocretin receptor 2 gene (Hcrtr 2) cause canine familial narcolepsy. In humans, mutations in hypocretin-related genes are rare, but cerebrospinal fluid (CSF) hypocretin-1 is undetectable in most sporadic c...
Main Authors: | Beth Ripley, Nobuhiro Fujiki, Mutsumi Okura, Emmanuel Mignot, Seiji Nishino |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2001-06-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996101903894 |
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