Evaluation of Intracerebral Hemorrhage Functional Outcome Score informativeness for identification of short-term vital outcome in patients with spontaneous supratentorial intracerebral haemorrhage
The main purpose of the study was to conduct the informative value of Intracerebral Hemorrhage Functional Outcome Score (ICH-FOS) assessment for the determination of a short-term vital prognosis in patients with spontaneous supratentorial intracerebral hemorrhage (SSICH). Materials and methods. A...
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| Format: | Article |
| Language: | English |
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Zaporozhye State Medical University
2018-12-01
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| Series: | Zaporožskij Medicinskij Žurnal |
| Subjects: | |
| Online Access: | http://zmj.zsmu.edu.ua/article/view/146536/148527 |
| _version_ | 1819140854402514944 |
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| author | A. A. Kuznietsov |
| author_facet | A. A. Kuznietsov |
| author_sort | A. A. Kuznietsov |
| collection | DOAJ |
| description | The main purpose of the study was to conduct the informative value of Intracerebral Hemorrhage Functional Outcome Score (ICH-FOS) assessment for the determination of a short-term vital prognosis in patients with spontaneous supratentorial intracerebral hemorrhage (SSICH).
Materials and methods. A prospective, cohort study was conducted among 191 patients (117 men and 74 women, the mean age was 65.1 ± 0.8 years) with SSICH treated in a conservative manner. This study included clinical assessment (National Institute of Health Stroke Scale, Glasgow Coma Scale), neuroimaging and biochemistry examination. The ICH-FOS was used in order to conduct a complex assessment of the patients’ state severity on admission. The functional outcome of the SSICH acute period was assessed on the 21st day of the disease in accordance with the modified Rankin Scale.
Results. Lethal outcome was noted in 22 patients (11.5 %). The patients with the lethal outcome during the acute period had a higher value of the ICH-FOS (8 (7–10) versus 4 (3–6), P < 0.0001) in the onset of SSICH. Based on a ROC-analysis it was determined that the ICH-FOS >6 is the predictor of the lethal outcome in the acute period of SSICH (Se = 77.3 %; Sp = 81.1 %; AUC ± SE (95 % CI) = 0.86 ± 0.04 (0.80–0.91), P < 0.0001). In the group of patients with the ICH-FOS value >6 (n = 49) lethal outcome was noted in 34.7 % of cases, whereas in the group of patients with the ICH-FOS value ≤6 (n = 142) it was noted only in 3.5 % of cases.
Conclusions. The Intracerebral Hemorrhage Functional Outcome Sсore is a highly informative tool for the determination of a short-term vital prognosis of SSICH acute period outcome. The ICH-FOS >6 is associated with a 9.9-fold increased risk of lethal outcome (RR 95 % CI 3.8–25.3, P < 0.0001). |
| first_indexed | 2024-12-22T11:45:10Z |
| format | Article |
| id | doaj.art-e272b84b082549e3ada691825b6292cc |
| institution | Directory Open Access Journal |
| issn | 2306-4145 2310-1210 |
| language | English |
| last_indexed | 2024-12-22T11:45:10Z |
| publishDate | 2018-12-01 |
| publisher | Zaporozhye State Medical University |
| record_format | Article |
| series | Zaporožskij Medicinskij Žurnal |
| spelling | doaj.art-e272b84b082549e3ada691825b6292cc2022-12-21T18:27:09ZengZaporozhye State Medical UniversityZaporožskij Medicinskij Žurnal2306-41452310-12102018-12-0120675275610.14739/2310-1210.2018.6.146536Evaluation of Intracerebral Hemorrhage Functional Outcome Score informativeness for identification of short-term vital outcome in patients with spontaneous supratentorial intracerebral haemorrhageA. A. KuznietsovThe main purpose of the study was to conduct the informative value of Intracerebral Hemorrhage Functional Outcome Score (ICH-FOS) assessment for the determination of a short-term vital prognosis in patients with spontaneous supratentorial intracerebral hemorrhage (SSICH). Materials and methods. A prospective, cohort study was conducted among 191 patients (117 men and 74 women, the mean age was 65.1 ± 0.8 years) with SSICH treated in a conservative manner. This study included clinical assessment (National Institute of Health Stroke Scale, Glasgow Coma Scale), neuroimaging and biochemistry examination. The ICH-FOS was used in order to conduct a complex assessment of the patients’ state severity on admission. The functional outcome of the SSICH acute period was assessed on the 21st day of the disease in accordance with the modified Rankin Scale. Results. Lethal outcome was noted in 22 patients (11.5 %). The patients with the lethal outcome during the acute period had a higher value of the ICH-FOS (8 (7–10) versus 4 (3–6), P < 0.0001) in the onset of SSICH. Based on a ROC-analysis it was determined that the ICH-FOS >6 is the predictor of the lethal outcome in the acute period of SSICH (Se = 77.3 %; Sp = 81.1 %; AUC ± SE (95 % CI) = 0.86 ± 0.04 (0.80–0.91), P < 0.0001). In the group of patients with the ICH-FOS value >6 (n = 49) lethal outcome was noted in 34.7 % of cases, whereas in the group of patients with the ICH-FOS value ≤6 (n = 142) it was noted only in 3.5 % of cases. Conclusions. The Intracerebral Hemorrhage Functional Outcome Sсore is a highly informative tool for the determination of a short-term vital prognosis of SSICH acute period outcome. The ICH-FOS >6 is associated with a 9.9-fold increased risk of lethal outcome (RR 95 % CI 3.8–25.3, P < 0.0001).http://zmj.zsmu.edu.ua/article/view/146536/148527cerebral hemorrhageX-Ray tomographymortalityprognosis |
| spellingShingle | A. A. Kuznietsov Evaluation of Intracerebral Hemorrhage Functional Outcome Score informativeness for identification of short-term vital outcome in patients with spontaneous supratentorial intracerebral haemorrhage Zaporožskij Medicinskij Žurnal cerebral hemorrhage X-Ray tomography mortality prognosis |
| title | Evaluation of Intracerebral Hemorrhage Functional Outcome Score informativeness for identification of short-term vital outcome in patients with spontaneous supratentorial intracerebral haemorrhage |
| title_full | Evaluation of Intracerebral Hemorrhage Functional Outcome Score informativeness for identification of short-term vital outcome in patients with spontaneous supratentorial intracerebral haemorrhage |
| title_fullStr | Evaluation of Intracerebral Hemorrhage Functional Outcome Score informativeness for identification of short-term vital outcome in patients with spontaneous supratentorial intracerebral haemorrhage |
| title_full_unstemmed | Evaluation of Intracerebral Hemorrhage Functional Outcome Score informativeness for identification of short-term vital outcome in patients with spontaneous supratentorial intracerebral haemorrhage |
| title_short | Evaluation of Intracerebral Hemorrhage Functional Outcome Score informativeness for identification of short-term vital outcome in patients with spontaneous supratentorial intracerebral haemorrhage |
| title_sort | evaluation of intracerebral hemorrhage functional outcome score informativeness for identification of short term vital outcome in patients with spontaneous supratentorial intracerebral haemorrhage |
| topic | cerebral hemorrhage X-Ray tomography mortality prognosis |
| url | http://zmj.zsmu.edu.ua/article/view/146536/148527 |
| work_keys_str_mv | AT aakuznietsov evaluationofintracerebralhemorrhagefunctionaloutcomescoreinformativenessforidentificationofshorttermvitaloutcomeinpatientswithspontaneoussupratentorialintracerebralhaemorrhage |