A Case Report: Rhino-Orbito-Cerebral Mucormycosis with visual impairment and cranial nerve palsies in a tertiary care hospital Sri Lanka

Mucormycosis is an angioinvasive infection, especially among immunocompromised patients. There are several forms of the disease and rhino-orbito-cerebral mucormycosis is the commonest presentation globally, especially among patients with diabetes mellitus with or without ketoacidosis. We report a pa...

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Main Authors: M. N. Pitagampola, F. S. Makeen, S. Chandrasiri, P. I. Jayasekara, C. S. P. Sosai, D. Jayasekara, M. Jayasinghe
Format: Article
Language:English
Published: Sri Lankan Society for Microbiology 2023-10-01
Series:Sri Lankan Journal of Infectious Diseases
Subjects:
Online Access:https://account.sljid.sljol.info/index.php/sljo-j-sljid/article/view/8588
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author M. N. Pitagampola
F. S. Makeen
S. Chandrasiri
P. I. Jayasekara
C. S. P. Sosai
D. Jayasekara
M. Jayasinghe
author_facet M. N. Pitagampola
F. S. Makeen
S. Chandrasiri
P. I. Jayasekara
C. S. P. Sosai
D. Jayasekara
M. Jayasinghe
author_sort M. N. Pitagampola
collection DOAJ
description Mucormycosis is an angioinvasive infection, especially among immunocompromised patients. There are several forms of the disease and rhino-orbito-cerebral mucormycosis is the commonest presentation globally, especially among patients with diabetes mellitus with or without ketoacidosis. We report a patient with rhino-orbito-cerebral mucormycosis involving multiple cranial nerve palsies. A 70-year-old female patient with uncontrolled diabetes mellitus presented with left periorbital swelling and reduced vision on the same side along with epistaxis. On examination, she was found to have multiple cranial nerve palsies. She was managed as rhino-orbito-cerebral mucormycosis after performing several microbiological, histological, and radiological tests. The patient was discharged after 4 months of hospital stay. Despite successful medical and surgical interventions, the patient died a week after being discharged from the hospital. Though we have no strong evidence, the disease itself, her co-morbidities, sepsis, and surgical trauma could have contributed to her death.
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spelling doaj.art-e27986d39cc042cd88184296805c9adf2023-12-12T08:10:58ZengSri Lankan Society for MicrobiologySri Lankan Journal of Infectious Diseases2012-81692448-96542023-10-01132E48:1510.4038/sljid.v13i2.8588243A Case Report: Rhino-Orbito-Cerebral Mucormycosis with visual impairment and cranial nerve palsies in a tertiary care hospital Sri LankaM. N. Pitagampola0https://orcid.org/0000-0002-3210-1135F. S. Makeen1S. Chandrasiri2P. I. Jayasekara3C. S. P. Sosai4D. Jayasekara5M. Jayasinghe6Colombo South Teaching Hospital, KalubowilaColombo South Teaching Hospital, KalubowilaColombo South Teaching Hospital, KalubowilaMedical Research Institute, ColomboColombo South Teaching Hospital, KalubowilaColombo South Teaching Hospital, KalubowilaColombo South Teaching Hospital, KalubowilaMucormycosis is an angioinvasive infection, especially among immunocompromised patients. There are several forms of the disease and rhino-orbito-cerebral mucormycosis is the commonest presentation globally, especially among patients with diabetes mellitus with or without ketoacidosis. We report a patient with rhino-orbito-cerebral mucormycosis involving multiple cranial nerve palsies. A 70-year-old female patient with uncontrolled diabetes mellitus presented with left periorbital swelling and reduced vision on the same side along with epistaxis. On examination, she was found to have multiple cranial nerve palsies. She was managed as rhino-orbito-cerebral mucormycosis after performing several microbiological, histological, and radiological tests. The patient was discharged after 4 months of hospital stay. Despite successful medical and surgical interventions, the patient died a week after being discharged from the hospital. Though we have no strong evidence, the disease itself, her co-morbidities, sepsis, and surgical trauma could have contributed to her death.https://account.sljid.sljol.info/index.php/sljo-j-sljid/article/view/8588mucormycosisdiabetescranial nerve palsiesrhizopus spamphotericin b
spellingShingle M. N. Pitagampola
F. S. Makeen
S. Chandrasiri
P. I. Jayasekara
C. S. P. Sosai
D. Jayasekara
M. Jayasinghe
A Case Report: Rhino-Orbito-Cerebral Mucormycosis with visual impairment and cranial nerve palsies in a tertiary care hospital Sri Lanka
Sri Lankan Journal of Infectious Diseases
mucormycosis
diabetes
cranial nerve palsies
rhizopus sp
amphotericin b
title A Case Report: Rhino-Orbito-Cerebral Mucormycosis with visual impairment and cranial nerve palsies in a tertiary care hospital Sri Lanka
title_full A Case Report: Rhino-Orbito-Cerebral Mucormycosis with visual impairment and cranial nerve palsies in a tertiary care hospital Sri Lanka
title_fullStr A Case Report: Rhino-Orbito-Cerebral Mucormycosis with visual impairment and cranial nerve palsies in a tertiary care hospital Sri Lanka
title_full_unstemmed A Case Report: Rhino-Orbito-Cerebral Mucormycosis with visual impairment and cranial nerve palsies in a tertiary care hospital Sri Lanka
title_short A Case Report: Rhino-Orbito-Cerebral Mucormycosis with visual impairment and cranial nerve palsies in a tertiary care hospital Sri Lanka
title_sort case report rhino orbito cerebral mucormycosis with visual impairment and cranial nerve palsies in a tertiary care hospital sri lanka
topic mucormycosis
diabetes
cranial nerve palsies
rhizopus sp
amphotericin b
url https://account.sljid.sljol.info/index.php/sljo-j-sljid/article/view/8588
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