A Multisite Non-Inferiority Randomized Controlled Trial of the Efficacy of Cognitive-Behavior Therapy for Generalized Anxiety Disorder Delivered by Videoconference
Delivering psychotherapy by videoconference has been studied in a number of clinical trials, but no large controlled trial has involved generalized anxiety disorder (GAD). This multicenter randomized controlled non-inferiority trial was conducted to test if cognitive-behavior psychotherapy delivered...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/19/5924 |
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| author | Stéphane Bouchard Michel J. Dugas Geneviève Belleville Frédéric Langlois Patrick Gosselin Geneviève Robillard Giulia Corno André Marchand |
| author_facet | Stéphane Bouchard Michel J. Dugas Geneviève Belleville Frédéric Langlois Patrick Gosselin Geneviève Robillard Giulia Corno André Marchand |
| author_sort | Stéphane Bouchard |
| collection | DOAJ |
| description | Delivering psychotherapy by videoconference has been studied in a number of clinical trials, but no large controlled trial has involved generalized anxiety disorder (GAD). This multicenter randomized controlled non-inferiority trial was conducted to test if cognitive-behavior psychotherapy delivered by videoconference (VCP) is as effective as cognitive-behavior psychotherapy delivered face-to-face, using a strict margin of tolerance for non-inferiority. A total of 148 adults received a 15-session weekly manualized program. The treatment was based on the intolerance of uncertainty model of GAD. The impact of treatment was assessed using primary (GAD severity), secondary (worry, anxiety, and intolerance of uncertainty) and tertiary (general functioning) variables measured before and after treatment and at 6-month and 12-month follow-ups. Results showed that: (a) the treatment was effective; (b) VCP for GAD was statistically non-inferior to face-to-face psychotherapy on primary, secondary and tertiary measures at all assessment points; (c) change in intolerance of uncertainty significantly predicted change in the primary outcome measure over and above important clinical factors common to all psychotherapies (motivation, working alliance, perceived therapist competence, and client satisfaction). These findings support the use of VCP as a promising treatment option for adults with GAD. Clinical trial registry: ISRCTN#12662027. |
| first_indexed | 2024-03-09T21:33:46Z |
| format | Article |
| id | doaj.art-e27a90c5263844d9b5a12492ed4e2e5b |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T21:33:46Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-e27a90c5263844d9b5a12492ed4e2e5b2023-11-23T20:51:06ZengMDPI AGJournal of Clinical Medicine2077-03832022-10-011119592410.3390/jcm11195924A Multisite Non-Inferiority Randomized Controlled Trial of the Efficacy of Cognitive-Behavior Therapy for Generalized Anxiety Disorder Delivered by VideoconferenceStéphane Bouchard0Michel J. Dugas1Geneviève Belleville2Frédéric Langlois3Patrick Gosselin4Geneviève Robillard5Giulia Corno6André Marchand7Département de Psychologie et de Psychoéducation, Université du Québec en Outaouais, Gatineau, QC J8X 3X7, CanadaDépartement de Psychologie et de Psychoéducation, Université du Québec en Outaouais, Gatineau, QC J8X 3X7, CanadaÉcole de Psychologie, Université Laval, Québec, QC G1V 0A6, CanadaDépartement de Psychologie, Université du Québec à Trois-Rivières, Trois-Rivières, QC G8Z 4M3, CanadaDépartement de Psychologie, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, CanadaDépartement de Psychologie et de Psychoéducation, Université du Québec en Outaouais, Gatineau, QC J8X 3X7, CanadaDépartement de Psychologie et de Psychoéducation, Université du Québec en Outaouais, Gatineau, QC J8X 3X7, CanadaDépartement de Psychologie, Université du Québec à Montréal, Montréal, QC H2L 2C4, CanadaDelivering psychotherapy by videoconference has been studied in a number of clinical trials, but no large controlled trial has involved generalized anxiety disorder (GAD). This multicenter randomized controlled non-inferiority trial was conducted to test if cognitive-behavior psychotherapy delivered by videoconference (VCP) is as effective as cognitive-behavior psychotherapy delivered face-to-face, using a strict margin of tolerance for non-inferiority. A total of 148 adults received a 15-session weekly manualized program. The treatment was based on the intolerance of uncertainty model of GAD. The impact of treatment was assessed using primary (GAD severity), secondary (worry, anxiety, and intolerance of uncertainty) and tertiary (general functioning) variables measured before and after treatment and at 6-month and 12-month follow-ups. Results showed that: (a) the treatment was effective; (b) VCP for GAD was statistically non-inferior to face-to-face psychotherapy on primary, secondary and tertiary measures at all assessment points; (c) change in intolerance of uncertainty significantly predicted change in the primary outcome measure over and above important clinical factors common to all psychotherapies (motivation, working alliance, perceived therapist competence, and client satisfaction). These findings support the use of VCP as a promising treatment option for adults with GAD. Clinical trial registry: ISRCTN#12662027.https://www.mdpi.com/2077-0383/11/19/5924videoconferencing psychotherapygeneralized anxiety disordercognitive-behavior therapynon-inferioritypredictors of outcome |
| spellingShingle | Stéphane Bouchard Michel J. Dugas Geneviève Belleville Frédéric Langlois Patrick Gosselin Geneviève Robillard Giulia Corno André Marchand A Multisite Non-Inferiority Randomized Controlled Trial of the Efficacy of Cognitive-Behavior Therapy for Generalized Anxiety Disorder Delivered by Videoconference Journal of Clinical Medicine videoconferencing psychotherapy generalized anxiety disorder cognitive-behavior therapy non-inferiority predictors of outcome |
| title | A Multisite Non-Inferiority Randomized Controlled Trial of the Efficacy of Cognitive-Behavior Therapy for Generalized Anxiety Disorder Delivered by Videoconference |
| title_full | A Multisite Non-Inferiority Randomized Controlled Trial of the Efficacy of Cognitive-Behavior Therapy for Generalized Anxiety Disorder Delivered by Videoconference |
| title_fullStr | A Multisite Non-Inferiority Randomized Controlled Trial of the Efficacy of Cognitive-Behavior Therapy for Generalized Anxiety Disorder Delivered by Videoconference |
| title_full_unstemmed | A Multisite Non-Inferiority Randomized Controlled Trial of the Efficacy of Cognitive-Behavior Therapy for Generalized Anxiety Disorder Delivered by Videoconference |
| title_short | A Multisite Non-Inferiority Randomized Controlled Trial of the Efficacy of Cognitive-Behavior Therapy for Generalized Anxiety Disorder Delivered by Videoconference |
| title_sort | multisite non inferiority randomized controlled trial of the efficacy of cognitive behavior therapy for generalized anxiety disorder delivered by videoconference |
| topic | videoconferencing psychotherapy generalized anxiety disorder cognitive-behavior therapy non-inferiority predictors of outcome |
| url | https://www.mdpi.com/2077-0383/11/19/5924 |
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