Human pulmonary artery endothelial cells upregulate ACE2 expression in response to iron‐regulatory elements: Potential implications for SARS‐CoV‐2 infection

Human pulmonary artery endothelial cells upregulate ACE2 expression in response to iron‐regulatory elements: Potential implications for SARS‐CoV‐2 infection

Abstract Vascular endothelial cell dysfunction is reported in severe coronavirus disease 2019 disease, however, controversy exists regarding levels of angiotensin‐converting enzyme 2 (ACE2) expression, a coreceptor for severe acute respiratory syndrome coronavirus 2, in these cells. We report ACE2 e...

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Bibliographic Details
Main Authors: Quezia K. Toe, Theo Issitt, Abdul Mahomed, Fatma Almaghlougth, Ishan Bahree, Charles Sturge, Xueqi Hu, Ioannis Panselinas, Anne Burke‐Gaffney, Stephen, Jc Wort, Gregory John Quinlan
Format: Article
Language:English
Published: Wiley 2022-04-01
Series:Pulmonary Circulation
Subjects:
COVID‐19
hepcidin/ferroportin axis
interleukin‐6
pulmonary artery endothelial cells
Online Access:https://doi.org/10.1002/pul2.12068

Internet

https://doi.org/10.1002/pul2.12068

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