Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding
Chronic kidney disease (CKD) is a very common chronic non-communicable disease. Phosphate and calcium metabolism disorders are one of the most common features of CKD. Sevelamer carbonate is the most widely used non-calcium phosphate binder. Gastrointestinal (GI) injury associated with sevelamer use...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1097469/full |
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| author | Margareta Fistrek Prlic Mislav Jelakovic Marko Brinar Marko Brinar Dora Grgic Ivan Romic Zlatko Marusic Ema Ivandic Bojan Jelakovic Bojan Jelakovic Ivana Vukovic Brinar Ivana Vukovic Brinar Zeljko Krznaric Zeljko Krznaric |
| author_facet | Margareta Fistrek Prlic Mislav Jelakovic Marko Brinar Marko Brinar Dora Grgic Ivan Romic Zlatko Marusic Ema Ivandic Bojan Jelakovic Bojan Jelakovic Ivana Vukovic Brinar Ivana Vukovic Brinar Zeljko Krznaric Zeljko Krznaric |
| author_sort | Margareta Fistrek Prlic |
| collection | DOAJ |
| description | Chronic kidney disease (CKD) is a very common chronic non-communicable disease. Phosphate and calcium metabolism disorders are one of the most common features of CKD. Sevelamer carbonate is the most widely used non-calcium phosphate binder. Gastrointestinal (GI) injury associated with sevelamer use is a documented adverse effect but is underrecognized as a cause of gastrointestinal symptoms in patients with CKD. We report a case of a 74-year-old woman taking low-dose sevelamer with serious gastrointestinal adverse effects causing colon rupture and severe gastrointestinal bleeding. |
| first_indexed | 2024-04-09T15:45:45Z |
| format | Article |
| id | doaj.art-e27b64eb2af047b68f9e9630af672a4c |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-09T15:45:45Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-e27b64eb2af047b68f9e9630af672a4c2023-04-27T04:28:41ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-04-011010.3389/fmed.2023.10974691097469Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleedingMargareta Fistrek Prlic0Mislav Jelakovic1Marko Brinar2Marko Brinar3Dora Grgic4Ivan Romic5Zlatko Marusic6Ema Ivandic7Bojan Jelakovic8Bojan Jelakovic9Ivana Vukovic Brinar10Ivana Vukovic Brinar11Zeljko Krznaric12Zeljko Krznaric13Department of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Center Zagreb, Zagreb, CroatiaDepartment of Gastroenterology, University Hospital Center Zagreb, Zagreb, CroatiaDepartment of Gastroenterology, University Hospital Center Zagreb, Zagreb, CroatiaSchool of Medicine, University of Zagreb, Zagreb, CroatiaDepartment of Gastroenterology, University Hospital Center Zagreb, Zagreb, CroatiaDepartment of Abdominal Surgery, University Hospital Center Zagreb, Zagreb, CroatiaDepartment of Pathology, University Hospital Center Zagreb, Zagreb, CroatiaDepartment of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Center Zagreb, Zagreb, CroatiaDepartment of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Center Zagreb, Zagreb, CroatiaSchool of Medicine, University of Zagreb, Zagreb, CroatiaDepartment of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Center Zagreb, Zagreb, CroatiaSchool of Medicine, University of Zagreb, Zagreb, CroatiaDepartment of Gastroenterology, University Hospital Center Zagreb, Zagreb, CroatiaSchool of Medicine, University of Zagreb, Zagreb, CroatiaChronic kidney disease (CKD) is a very common chronic non-communicable disease. Phosphate and calcium metabolism disorders are one of the most common features of CKD. Sevelamer carbonate is the most widely used non-calcium phosphate binder. Gastrointestinal (GI) injury associated with sevelamer use is a documented adverse effect but is underrecognized as a cause of gastrointestinal symptoms in patients with CKD. We report a case of a 74-year-old woman taking low-dose sevelamer with serious gastrointestinal adverse effects causing colon rupture and severe gastrointestinal bleeding.https://www.frontiersin.org/articles/10.3389/fmed.2023.1097469/fullgastrointestinal lesiongastrointestinal bleedingcolon rupturechronic kidney diseasesevelamer carbonatecase report |
| spellingShingle | Margareta Fistrek Prlic Mislav Jelakovic Marko Brinar Marko Brinar Dora Grgic Ivan Romic Zlatko Marusic Ema Ivandic Bojan Jelakovic Bojan Jelakovic Ivana Vukovic Brinar Ivana Vukovic Brinar Zeljko Krznaric Zeljko Krznaric Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding Frontiers in Medicine gastrointestinal lesion gastrointestinal bleeding colon rupture chronic kidney disease sevelamer carbonate case report |
| title | Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding |
| title_full | Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding |
| title_fullStr | Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding |
| title_full_unstemmed | Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding |
| title_short | Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding |
| title_sort | case report sevelamer associated colitis a cause of pseudotumor formation with colon perforation and life threatening bleeding |
| topic | gastrointestinal lesion gastrointestinal bleeding colon rupture chronic kidney disease sevelamer carbonate case report |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1097469/full |
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