BURKITT LYMPHOMA PRESENTING WITH EYE AND KIDNEY INVOLVEMENT: CASE REPORT
Case report: Burkitt lymphoma (BL) is an aggressive form of B-cell non-Hodgkin lymphoma. It may present with a variety of symptoms leading to possible misdiagnosis and delay in treatment. BL is fatal if left untreated, and early diagnosis and treatment can improve prognosis. In this case report, a 3...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-11-01
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| Series: | Hematology, Transfusion and Cell Therapy |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2531137921011482 |
| _version_ | 1818567001977651200 |
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| author | Aslı Turgutoğlu Yılmaz Derya Ozyoruk Neriman Sarı F.Burcin Kurtipek Arzu Erdem Selma Cakmakci Sonay Incesoy Inci Ilhan Ergurhan |
| author_facet | Aslı Turgutoğlu Yılmaz Derya Ozyoruk Neriman Sarı F.Burcin Kurtipek Arzu Erdem Selma Cakmakci Sonay Incesoy Inci Ilhan Ergurhan |
| author_sort | Aslı Turgutoğlu Yılmaz |
| collection | DOAJ |
| description | Case report: Burkitt lymphoma (BL) is an aggressive form of B-cell non-Hodgkin lymphoma. It may present with a variety of symptoms leading to possible misdiagnosis and delay in treatment. BL is fatal if left untreated, and early diagnosis and treatment can improve prognosis. In this case report, a 3.5-year-old male patient with no known disease had left eyelid swelling and hematuria, and orbital magnetic resonance imaging performed after his admission showed contrast enhancement in the bulbus oculi, and increased uptake in both kidneys (suvmax:9.5) in positron emission tomography. The patient's bone marrow aspiration was normal. There was no involvement in the evaluation of the central nervous system. As a result of kidney biopsy, he was diagnosed with high-grade B-cell lymphoproliferative disease (Ki-67 95-100%, diffuse positivity with CD79a and EBV). Burkitt lymphoma. The treatment of the patient was started in the NHL-BFM 2012 R4 arm. At the end of the treatment, the ocular findings regressed. Burkitt lymphoma may present with different clinical presentations. If appropriate and rapid imaging techniques are used, positive results on survival can be obtained. Our patient is being followed up alive and well. |
| first_indexed | 2024-12-14T06:17:51Z |
| format | Article |
| id | doaj.art-e27d0734015c46569a194b068eee6941 |
| institution | Directory Open Access Journal |
| issn | 2531-1379 |
| language | English |
| last_indexed | 2024-12-14T06:17:51Z |
| publishDate | 2021-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Hematology, Transfusion and Cell Therapy |
| spelling | doaj.art-e27d0734015c46569a194b068eee69412022-12-21T23:13:59ZengElsevierHematology, Transfusion and Cell Therapy2531-13792021-11-0143S29BURKITT LYMPHOMA PRESENTING WITH EYE AND KIDNEY INVOLVEMENT: CASE REPORTAslı Turgutoğlu Yılmaz0Derya Ozyoruk1Neriman Sarı2F.Burcin Kurtipek3Arzu Erdem4Selma Cakmakci5Sonay Incesoy6Inci Ilhan Ergurhan7Department of Pediatric Hematology/Oncology, Ankara City Hospital Children's HospitalDepartment of Pediatric Hematology/Oncology, Ankara City Hospital Children's HospitalDepartment of Pediatric Hematology/Oncology, Ankara City Hospital Children's HospitalDepartment of Pediatric Hematology/Oncology, Ankara City Hospital Children's HospitalDepartment of Pediatric Hematology/Oncology, Ankara City Hospital Children's HospitalDepartment of Pediatric Hematology/Oncology, Ankara City Hospital Children's HospitalDepartment of Pediatric Hematology/Oncology, Ankara City Hospital Children's HospitalDepartment of Pediatric Hematology/Oncology, Ankara City Hospital Children's HospitalCase report: Burkitt lymphoma (BL) is an aggressive form of B-cell non-Hodgkin lymphoma. It may present with a variety of symptoms leading to possible misdiagnosis and delay in treatment. BL is fatal if left untreated, and early diagnosis and treatment can improve prognosis. In this case report, a 3.5-year-old male patient with no known disease had left eyelid swelling and hematuria, and orbital magnetic resonance imaging performed after his admission showed contrast enhancement in the bulbus oculi, and increased uptake in both kidneys (suvmax:9.5) in positron emission tomography. The patient's bone marrow aspiration was normal. There was no involvement in the evaluation of the central nervous system. As a result of kidney biopsy, he was diagnosed with high-grade B-cell lymphoproliferative disease (Ki-67 95-100%, diffuse positivity with CD79a and EBV). Burkitt lymphoma. The treatment of the patient was started in the NHL-BFM 2012 R4 arm. At the end of the treatment, the ocular findings regressed. Burkitt lymphoma may present with different clinical presentations. If appropriate and rapid imaging techniques are used, positive results on survival can be obtained. Our patient is being followed up alive and well.http://www.sciencedirect.com/science/article/pii/S2531137921011482 |
| spellingShingle | Aslı Turgutoğlu Yılmaz Derya Ozyoruk Neriman Sarı F.Burcin Kurtipek Arzu Erdem Selma Cakmakci Sonay Incesoy Inci Ilhan Ergurhan BURKITT LYMPHOMA PRESENTING WITH EYE AND KIDNEY INVOLVEMENT: CASE REPORT Hematology, Transfusion and Cell Therapy |
| title | BURKITT LYMPHOMA PRESENTING WITH EYE AND KIDNEY INVOLVEMENT: CASE REPORT |
| title_full | BURKITT LYMPHOMA PRESENTING WITH EYE AND KIDNEY INVOLVEMENT: CASE REPORT |
| title_fullStr | BURKITT LYMPHOMA PRESENTING WITH EYE AND KIDNEY INVOLVEMENT: CASE REPORT |
| title_full_unstemmed | BURKITT LYMPHOMA PRESENTING WITH EYE AND KIDNEY INVOLVEMENT: CASE REPORT |
| title_short | BURKITT LYMPHOMA PRESENTING WITH EYE AND KIDNEY INVOLVEMENT: CASE REPORT |
| title_sort | burkitt lymphoma presenting with eye and kidney involvement case report |
| url | http://www.sciencedirect.com/science/article/pii/S2531137921011482 |
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