The NLRP3 Inflammasome Is Dispensable in Methicillin-Resistant <i>Staphylococcus aureus</i> Urinary Tract Infection

The NLRP3 inflammasome is a cytoplasmic complex that senses molecular patterns from pathogens or damaged cells to trigger an innate immune defense response marked by the production of proinflammatory cytokines IL-1β and IL-18 and an inflammatory death called pyroptosis. The NLRP3 inflammasome is act...

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Bibliographic Details
Main Authors: Santosh Paudel, Rahul Kumar, Kenneth A. Rogers, Yogesh Saini, Sonika Patial, Ritwij Kulkarni
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/13/2/106