Kilovoltage projection streaming-based tracking application (KiPSTA): First clinical implementation during spine stereotactic radiation surgery
Purpose: This study aimed to develop a linac-mounted kilovoltage (kV) projection streaming-based tracking method for vertebral targets during spine stereotactic radiation surgery and evaluate the clinical feasibility of the proposed spine tracking method. Methods and materials: Using real-time kV pr...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-10-01
|
| Series: | Advances in Radiation Oncology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452109418300885 |
| _version_ | 1828381087559057408 |
|---|---|
| author | Jihun Kim, PhD Yang-Kyun Park, PhD David Edmunds, PhD Kevin Oh, MD Gregory C. Sharp, PhD Brian Winey, PhD |
| author_facet | Jihun Kim, PhD Yang-Kyun Park, PhD David Edmunds, PhD Kevin Oh, MD Gregory C. Sharp, PhD Brian Winey, PhD |
| author_sort | Jihun Kim, PhD |
| collection | DOAJ |
| description | Purpose: This study aimed to develop a linac-mounted kilovoltage (kV) projection streaming-based tracking method for vertebral targets during spine stereotactic radiation surgery and evaluate the clinical feasibility of the proposed spine tracking method. Methods and materials: Using real-time kV projection streaming within XVI (Elekta XVI), kV–projection-based tracking was applied to the target vertebral bodies. Two-dimensional in-plane patient translation was calculated via an image registration between digitally reconstructed radiographs (DRRs) and kV projections. DRR was generated from the cone beam computed tomography (CBCT) scan, which was obtained immediately before the tracking session. During a tracking session, each kV projection was streamed for an intensity gradient-based image with similar metric-based registration to the offset DRR. The ground truth displacement for each kV beam angle was calculated at the beam isocenter using the 6 degrees-of-freedom transformation that was obtained by a CBCT-CBCT rigid registration. The resulting translation by the DRR-projection registration was compared with the ground truth displacement. The proposed tracking method was evaluated retrospectively and online, using 7 and 5 spine patients, respectively. Results: The accuracy and precision of spine tracking for in-plane patient motion were 0.5 ± 0.2 and 0.2 ± 0.1 mm. The magnitude of patient motion that was estimated using the CBCT-CBCT rigid registration was (0.5 ± 0.4, 0.4 ± 0.3, 0.3 ± 0.3) mm and (0.3 ± 0.4, 0.2 ± 0.2, 0.5 ± 0.6) mm for all tracking sessions. The intrafraction motion was within 2 mm for all CBCT scans considered. Conclusions: This study demonstrated that the proposed spine tracking method can track intrafraction motion with sub-millimeter accuracy and precision, and sub-second latency. |
| first_indexed | 2024-12-10T04:09:52Z |
| format | Article |
| id | doaj.art-e27e335df18241e08cf119cd4505efe2 |
| institution | Directory Open Access Journal |
| issn | 2452-1094 |
| language | English |
| last_indexed | 2024-12-10T04:09:52Z |
| publishDate | 2018-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Advances in Radiation Oncology |
| spelling | doaj.art-e27e335df18241e08cf119cd4505efe22022-12-22T02:02:46ZengElsevierAdvances in Radiation Oncology2452-10942018-10-0134682692Kilovoltage projection streaming-based tracking application (KiPSTA): First clinical implementation during spine stereotactic radiation surgeryJihun Kim, PhD0Yang-Kyun Park, PhD1David Edmunds, PhD2Kevin Oh, MD3Gregory C. Sharp, PhD4Brian Winey, PhD5Department of Radiation Oncology, Yonsei Cancer Center, Seoul, South Korea; Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MassachusettsDepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TexasDepartment of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MassachusettsDepartment of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MassachusettsDepartment of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MassachusettsDepartment of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Corresponding author. Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, 30 Fruit Street, Boston, MA 02114.Purpose: This study aimed to develop a linac-mounted kilovoltage (kV) projection streaming-based tracking method for vertebral targets during spine stereotactic radiation surgery and evaluate the clinical feasibility of the proposed spine tracking method. Methods and materials: Using real-time kV projection streaming within XVI (Elekta XVI), kV–projection-based tracking was applied to the target vertebral bodies. Two-dimensional in-plane patient translation was calculated via an image registration between digitally reconstructed radiographs (DRRs) and kV projections. DRR was generated from the cone beam computed tomography (CBCT) scan, which was obtained immediately before the tracking session. During a tracking session, each kV projection was streamed for an intensity gradient-based image with similar metric-based registration to the offset DRR. The ground truth displacement for each kV beam angle was calculated at the beam isocenter using the 6 degrees-of-freedom transformation that was obtained by a CBCT-CBCT rigid registration. The resulting translation by the DRR-projection registration was compared with the ground truth displacement. The proposed tracking method was evaluated retrospectively and online, using 7 and 5 spine patients, respectively. Results: The accuracy and precision of spine tracking for in-plane patient motion were 0.5 ± 0.2 and 0.2 ± 0.1 mm. The magnitude of patient motion that was estimated using the CBCT-CBCT rigid registration was (0.5 ± 0.4, 0.4 ± 0.3, 0.3 ± 0.3) mm and (0.3 ± 0.4, 0.2 ± 0.2, 0.5 ± 0.6) mm for all tracking sessions. The intrafraction motion was within 2 mm for all CBCT scans considered. Conclusions: This study demonstrated that the proposed spine tracking method can track intrafraction motion with sub-millimeter accuracy and precision, and sub-second latency.http://www.sciencedirect.com/science/article/pii/S2452109418300885 |
| spellingShingle | Jihun Kim, PhD Yang-Kyun Park, PhD David Edmunds, PhD Kevin Oh, MD Gregory C. Sharp, PhD Brian Winey, PhD Kilovoltage projection streaming-based tracking application (KiPSTA): First clinical implementation during spine stereotactic radiation surgery Advances in Radiation Oncology |
| title | Kilovoltage projection streaming-based tracking application (KiPSTA): First clinical implementation during spine stereotactic radiation surgery |
| title_full | Kilovoltage projection streaming-based tracking application (KiPSTA): First clinical implementation during spine stereotactic radiation surgery |
| title_fullStr | Kilovoltage projection streaming-based tracking application (KiPSTA): First clinical implementation during spine stereotactic radiation surgery |
| title_full_unstemmed | Kilovoltage projection streaming-based tracking application (KiPSTA): First clinical implementation during spine stereotactic radiation surgery |
| title_short | Kilovoltage projection streaming-based tracking application (KiPSTA): First clinical implementation during spine stereotactic radiation surgery |
| title_sort | kilovoltage projection streaming based tracking application kipsta first clinical implementation during spine stereotactic radiation surgery |
| url | http://www.sciencedirect.com/science/article/pii/S2452109418300885 |
| work_keys_str_mv | AT jihunkimphd kilovoltageprojectionstreamingbasedtrackingapplicationkipstafirstclinicalimplementationduringspinestereotacticradiationsurgery AT yangkyunparkphd kilovoltageprojectionstreamingbasedtrackingapplicationkipstafirstclinicalimplementationduringspinestereotacticradiationsurgery AT davidedmundsphd kilovoltageprojectionstreamingbasedtrackingapplicationkipstafirstclinicalimplementationduringspinestereotacticradiationsurgery AT kevinohmd kilovoltageprojectionstreamingbasedtrackingapplicationkipstafirstclinicalimplementationduringspinestereotacticradiationsurgery AT gregorycsharpphd kilovoltageprojectionstreamingbasedtrackingapplicationkipstafirstclinicalimplementationduringspinestereotacticradiationsurgery AT brianwineyphd kilovoltageprojectionstreamingbasedtrackingapplicationkipstafirstclinicalimplementationduringspinestereotacticradiationsurgery |