Correcting the Bias Correction for the Bootstrap Confidence Interval in Mediation Analysis

The bias-corrected bootstrap confidence interval (BCBCI) was once the method of choice for conducting inference on the indirect effect in mediation analysis due to its high power in small samples, but now it is criticized by methodologists for its inflated type I error rates. In its place, the perce...

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Main Authors: Tristan D. Tibbe, Amanda K. Montoya
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Psychology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyg.2022.810258/full
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author Tristan D. Tibbe
Amanda K. Montoya
author_facet Tristan D. Tibbe
Amanda K. Montoya
author_sort Tristan D. Tibbe
collection DOAJ
description The bias-corrected bootstrap confidence interval (BCBCI) was once the method of choice for conducting inference on the indirect effect in mediation analysis due to its high power in small samples, but now it is criticized by methodologists for its inflated type I error rates. In its place, the percentile bootstrap confidence interval (PBCI), which does not adjust for bias, is currently the recommended inferential method for indirect effects. This study proposes two alternative bias-corrected bootstrap methods for creating confidence intervals around the indirect effect: one originally used by Stine (1989) with the correlation coefficient, and a novel method that implements a reduced version of the BCBCI's bias correction. Using a Monte Carlo simulation, these methods were compared to the BCBCI, PBCI, and Chen and Fritz (2021)'s 30% Winsorized BCBCI. The results showed that the methods perform on a continuum, where the BCBCI has the best balance (i.e., having closest to an equal proportion of CIs falling above and below the true effect), highest power, and highest type I error rate; the PBCI has the worst balance, lowest power, and lowest type I error rate; and the alternative bias-corrected methods fall between these two methods on all three performance criteria. An extension of the original simulation that compared the bias-corrected methods to the PBCI after controlling for type I error rate inflation suggests that the increased power of these methods might only be due to their higher type I error rates. Thus, if control over the type I error rate is desired, the PBCI is still the recommended method for use with the indirect effect. Future research should examine the performance of these methods in the presence of missing data, confounding variables, and other real-world complications to enhance the generalizability of these results.
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spelling doaj.art-e281f262c9ec416b9dea956046721ea12022-12-22T03:35:22ZengFrontiers Media S.A.Frontiers in Psychology1664-10782022-05-011310.3389/fpsyg.2022.810258810258Correcting the Bias Correction for the Bootstrap Confidence Interval in Mediation AnalysisTristan D. TibbeAmanda K. MontoyaThe bias-corrected bootstrap confidence interval (BCBCI) was once the method of choice for conducting inference on the indirect effect in mediation analysis due to its high power in small samples, but now it is criticized by methodologists for its inflated type I error rates. In its place, the percentile bootstrap confidence interval (PBCI), which does not adjust for bias, is currently the recommended inferential method for indirect effects. This study proposes two alternative bias-corrected bootstrap methods for creating confidence intervals around the indirect effect: one originally used by Stine (1989) with the correlation coefficient, and a novel method that implements a reduced version of the BCBCI's bias correction. Using a Monte Carlo simulation, these methods were compared to the BCBCI, PBCI, and Chen and Fritz (2021)'s 30% Winsorized BCBCI. The results showed that the methods perform on a continuum, where the BCBCI has the best balance (i.e., having closest to an equal proportion of CIs falling above and below the true effect), highest power, and highest type I error rate; the PBCI has the worst balance, lowest power, and lowest type I error rate; and the alternative bias-corrected methods fall between these two methods on all three performance criteria. An extension of the original simulation that compared the bias-corrected methods to the PBCI after controlling for type I error rate inflation suggests that the increased power of these methods might only be due to their higher type I error rates. Thus, if control over the type I error rate is desired, the PBCI is still the recommended method for use with the indirect effect. Future research should examine the performance of these methods in the presence of missing data, confounding variables, and other real-world complications to enhance the generalizability of these results.https://www.frontiersin.org/articles/10.3389/fpsyg.2022.810258/fullbias-corrected bootstrap confidence intervalindirect effectbias correctiontype I error ratepowermediation
spellingShingle Tristan D. Tibbe
Amanda K. Montoya
Correcting the Bias Correction for the Bootstrap Confidence Interval in Mediation Analysis
Frontiers in Psychology
bias-corrected bootstrap confidence interval
indirect effect
bias correction
type I error rate
power
mediation
title Correcting the Bias Correction for the Bootstrap Confidence Interval in Mediation Analysis
title_full Correcting the Bias Correction for the Bootstrap Confidence Interval in Mediation Analysis
title_fullStr Correcting the Bias Correction for the Bootstrap Confidence Interval in Mediation Analysis
title_full_unstemmed Correcting the Bias Correction for the Bootstrap Confidence Interval in Mediation Analysis
title_short Correcting the Bias Correction for the Bootstrap Confidence Interval in Mediation Analysis
title_sort correcting the bias correction for the bootstrap confidence interval in mediation analysis
topic bias-corrected bootstrap confidence interval
indirect effect
bias correction
type I error rate
power
mediation
url https://www.frontiersin.org/articles/10.3389/fpsyg.2022.810258/full
work_keys_str_mv AT tristandtibbe correctingthebiascorrectionforthebootstrapconfidenceintervalinmediationanalysis
AT amandakmontoya correctingthebiascorrectionforthebootstrapconfidenceintervalinmediationanalysis