Efficient Synthesis of 3-Sulfonyl-2-sulfonylmethyl-2<i>H</i>-chromenes via Tandem Knoevenagel Condensation/Oxa-Michael Addition Protocol

Efficient Synthesis of 3-Sulfonyl-2-sulfonylmethyl-2<i>H</i>-chromenes via Tandem Knoevenagel Condensation/Oxa-Michael Addition Protocol

An organocatalytic [4 + 2] cascade annulation of salicylaldehydes and 1,3-bisarylsulfonylpropenes has been developed. This protocol enables the efficient and straightforward synthesis of a new series of 3-sulfonyl-2-sulfonylmethyl-2<i>H</i>-chromenes that are useful for exploring pharmac...

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Bibliographic Details
Main Authors: Lin Jiang, Peiying Peng, Min Li, Lu Li, Menglin Zhao, Minglong Yuan, Mingwei Yuan
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Catalysts
Subjects:
2<i>H</i>-chromene
[4 + 2] annulation
salicylaldehyde
1,3-bisarylsulfonylpropene
organocatalysis
Online Access:https://www.mdpi.com/2073-4344/12/5/491

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https://www.mdpi.com/2073-4344/12/5/491

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