Efficient Synthesis of 3-Sulfonyl-2-sulfonylmethyl-2<i>H</i>-chromenes via Tandem Knoevenagel Condensation/Oxa-Michael Addition Protocol

Efficient Synthesis of 3-Sulfonyl-2-sulfonylmethyl-2<i>H</i>-chromenes via Tandem Knoevenagel Condensation/Oxa-Michael Addition Protocol

An organocatalytic [4 + 2] cascade annulation of salicylaldehydes and 1,3-bisarylsulfonylpropenes has been developed. This protocol enables the efficient and straightforward synthesis of a new series of 3-sulfonyl-2-sulfonylmethyl-2<i>H</i>-chromenes that are useful for exploring pharmac...

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Bibliographic Details
Main Authors:	Lin Jiang, Peiying Peng, Min Li, Lu Li, Menglin Zhao, Minglong Yuan, Mingwei Yuan
Format:	Article
Language:	English
Published:	MDPI AG 2022-04-01
Series:	Catalysts
Subjects:	2<i>H</i>-chromene [4 + 2] annulation salicylaldehyde 1,3-bisarylsulfonylpropene organocatalysis
Online Access:	https://www.mdpi.com/2073-4344/12/5/491

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