Galangin/β-Cyclodextrin Inclusion Complex as a Drug-Delivery System for Improved Solubility and Biocompatibility in Breast Cancer Treatment

Galangin/β-Cyclodextrin Inclusion Complex as a Drug-Delivery System for Improved Solubility and Biocompatibility in Breast Cancer Treatment

The purpose of this study was to evaluate the potential of a newly modified cyclodextrin derivative, water-soluble β-cyclodextrin–epichlorohydrin (β-CD), as an effective drug carrier to enhance the poor solubility and bioavailability of galangin (GAL), a poorly water-soluble model drug. In this rega...

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Bibliographic Details
Main Authors: Zainab S. Abbas, Ghassan M. Sulaiman, Majid S. Jabir, Salman A. A. Mohammed, Riaz A. Khan, Hamdoon A. Mohammed, Amal Al-Subaiyel
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
galangin
β-cyclodextrin
drug delivery
biocompatibility
cytotoxicity
caspase-3 pathway
Online Access:https://www.mdpi.com/1420-3049/27/14/4521

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