Comparison of irinotecan and oxaliplatin as the first-line therapies for metastatic colorectal cancer: a meta-analysis

Comparison of irinotecan and oxaliplatin as the first-line therapies for metastatic colorectal cancer: a meta-analysis

Abstract Background Irinotecan (IRI) and oxaliplatin (Ox) are standard therapeutic agents of the first-line treatments for metastatic colorectal cancer (mCRC). Previous meta-analyses of randomized controlled trials (RCTs) showed that treatment with Ox-based compared with IRI-based regimens was assoc...

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Bibliographic Details
Main Authors: Sadayuki Kawai, Nozomi Takeshima, Yu Hayasaka, Akifumi Notsu, Mutsumi Yamazaki, Takanori Kawabata, Kentaro Yamazaki, Keita Mori, Hirofumi Yasui
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Cancer
Subjects:
Meta-analysis
Metastatic colorectal cancer
Chemotherapy
Online Access:https://doi.org/10.1186/s12885-021-07823-7

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