Silicon Oxycarbide Porous Particles and Film Coating as Strategies for Tenofovir Controlled Release in Vaginal Tablets for HIV Prevention

Silicon Oxycarbide Porous Particles and Film Coating as Strategies for Tenofovir Controlled Release in Vaginal Tablets for HIV Prevention

Sustained release of antiretroviral drugs is currently the most encouraging strategy for the prevention of the sexual transmission of HIV. Vaginal tablets based on hydrophilic gelling polymers are an interesting dosage form for this purpose, since they can be developed to modify the release of the d...

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Bibliographic Details
Main Authors: Araceli Martín-Illana, Raúl Cazorla-Luna, Fernando Notario-Pérez, Roberto Ruiz-Caro, Juan Rubio, Aitana Tamayo, María Dolores Veiga
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceutics
Subjects:
AIDS
antiviral therapy
chitosan
hydroxypropyl methylcellulose
mucoadhesion
pre-exposure prophylaxis
Online Access:https://www.mdpi.com/1999-4923/14/8/1567

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