Steviol Glycosides from <i>Stevia rebaudiana</i>: An Updated Overview of Their Sweetening Activity, Pharmacological Properties, and Safety Aspects
This literature-based review synthesizes the available scientific information about steviol glycosides as natural sweeteners and molecules with therapeutic potential. In addition, it discusses the safety concerns regarding human consumption. Steviol glycosides exhibit a superior sweetener proficienc...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-01-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/28/3/1258 |
| _version_ | 1797623794352783360 |
|---|---|
| author | Adriana Monserrath Orellana-Paucar |
| author_facet | Adriana Monserrath Orellana-Paucar |
| author_sort | Adriana Monserrath Orellana-Paucar |
| collection | DOAJ |
| description | This literature-based review synthesizes the available scientific information about steviol glycosides as natural sweeteners and molecules with therapeutic potential. In addition, it discusses the safety concerns regarding human consumption. Steviol glycosides exhibit a superior sweetener proficiency to that of sucrose and are noncaloric, noncariogenic, and nonfermentative. Scientific evidence encourages stevioside and rebaudioside A as sweetener alternatives to sucrose and supports their use based on their absences of harmful effects on human health. Moreover, these active compounds isolated from <i>Stevia rebaudiana</i> possess interesting medicinal activities, including antidiabetic, antihypertensive, anti-inflammatory, antioxidant, anticancer, and antidiarrheal activity. The described bioactivities of steviol glycosides deserve special attention based on their dose dependence and specific pathological situations. Further clinical research is needed to understand underlying mechanisms of action, therapeutic indexes, and pharmacological applications. |
| first_indexed | 2024-03-11T09:33:48Z |
| format | Article |
| id | doaj.art-e295fcf9235c4fe195e6093b57e8e326 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-11T09:33:48Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-e295fcf9235c4fe195e6093b57e8e3262023-11-16T17:29:53ZengMDPI AGMolecules1420-30492023-01-01283125810.3390/molecules28031258Steviol Glycosides from <i>Stevia rebaudiana</i>: An Updated Overview of Their Sweetening Activity, Pharmacological Properties, and Safety AspectsAdriana Monserrath Orellana-Paucar0Nutrition and Dietetics School, Faculty of Medical Sciences, University of Cuenca, Cuenca 010204, EcuadorThis literature-based review synthesizes the available scientific information about steviol glycosides as natural sweeteners and molecules with therapeutic potential. In addition, it discusses the safety concerns regarding human consumption. Steviol glycosides exhibit a superior sweetener proficiency to that of sucrose and are noncaloric, noncariogenic, and nonfermentative. Scientific evidence encourages stevioside and rebaudioside A as sweetener alternatives to sucrose and supports their use based on their absences of harmful effects on human health. Moreover, these active compounds isolated from <i>Stevia rebaudiana</i> possess interesting medicinal activities, including antidiabetic, antihypertensive, anti-inflammatory, antioxidant, anticancer, and antidiarrheal activity. The described bioactivities of steviol glycosides deserve special attention based on their dose dependence and specific pathological situations. Further clinical research is needed to understand underlying mechanisms of action, therapeutic indexes, and pharmacological applications.https://www.mdpi.com/1420-3049/28/3/1258<i>Stevia rebaudiana</i>steviasteviol glycosidessweetenerbioactivitysafety |
| spellingShingle | Adriana Monserrath Orellana-Paucar Steviol Glycosides from <i>Stevia rebaudiana</i>: An Updated Overview of Their Sweetening Activity, Pharmacological Properties, and Safety Aspects Molecules <i>Stevia rebaudiana</i> stevia steviol glycosides sweetener bioactivity safety |
| title | Steviol Glycosides from <i>Stevia rebaudiana</i>: An Updated Overview of Their Sweetening Activity, Pharmacological Properties, and Safety Aspects |
| title_full | Steviol Glycosides from <i>Stevia rebaudiana</i>: An Updated Overview of Their Sweetening Activity, Pharmacological Properties, and Safety Aspects |
| title_fullStr | Steviol Glycosides from <i>Stevia rebaudiana</i>: An Updated Overview of Their Sweetening Activity, Pharmacological Properties, and Safety Aspects |
| title_full_unstemmed | Steviol Glycosides from <i>Stevia rebaudiana</i>: An Updated Overview of Their Sweetening Activity, Pharmacological Properties, and Safety Aspects |
| title_short | Steviol Glycosides from <i>Stevia rebaudiana</i>: An Updated Overview of Their Sweetening Activity, Pharmacological Properties, and Safety Aspects |
| title_sort | steviol glycosides from i stevia rebaudiana i an updated overview of their sweetening activity pharmacological properties and safety aspects |
| topic | <i>Stevia rebaudiana</i> stevia steviol glycosides sweetener bioactivity safety |
| url | https://www.mdpi.com/1420-3049/28/3/1258 |
| work_keys_str_mv | AT adrianamonserrathorellanapaucar steviolglycosidesfromisteviarebaudianaianupdatedoverviewoftheirsweeteningactivitypharmacologicalpropertiesandsafetyaspects |