Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A
The objective of this study was to identify features of the system of lipid peroxidation - antioxidant protection in 31 women of reproductive age with viral hepatitis A. In women with hepatitis A virus (HAV) (main group) there is an increase in the level of double bonds (31,1%) and active products r...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Scientific Сentre for Family Health and Human Reproduction Problems
2015-02-01
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| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/2 |
| _version_ | 1797237515604721664 |
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| author | B. Ya. Vlasov M. A. Rashidova L. F. Sholokhov O. A. Vanteeva E. L. Chudinova |
| author_facet | B. Ya. Vlasov M. A. Rashidova L. F. Sholokhov O. A. Vanteeva E. L. Chudinova |
| author_sort | B. Ya. Vlasov |
| collection | DOAJ |
| description | The objective of this study was to identify features of the system of lipid peroxidation - antioxidant protection in 31 women of reproductive age with viral hepatitis A. In women with hepatitis A virus (HAV) (main group) there is an increase in the level of double bonds (31,1%) and active products reacting with thiobarbituric acid (141,7%) with a simultaneous decrease in the content of diene conjugates (69,4%), compared with the same indicators in the control group. The level of antioxidant protection in women in main group unlike the control was characterized by a decrease in total antioxidant activity (25,2%), by the inhibition of the activity of superoxide dismutase (29,1%), by decreasing the concentration of a-tocopherol (42,6%) on the background of increase of retinol level (184,6%). In general, the combination of prooxidant and antioxidant factors at HAV can be considered as a condition of oxidative stress (p < 0,05). |
| first_indexed | 2024-03-08T12:20:23Z |
| format | Article |
| id | doaj.art-e2974653fda546ac8275eff2e106f57d |
| institution | Directory Open Access Journal |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| last_indexed | 2024-04-24T17:20:59Z |
| publishDate | 2015-02-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj.art-e2974653fda546ac8275eff2e106f57d2024-03-28T07:49:13ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962015-02-01017102Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis AB. Ya. Vlasov0M. A. Rashidova1L. F. Sholokhov2O. A. Vanteeva3E. L. Chudinova4Scientific Centre for the Family Health and Human Reproduction ProblemsScientific Centre for the Family Health and Human Reproduction ProblemsScientific Centre for the Family Health and Human Reproduction ProblemsScientific Centre for the Family Health and Human Reproduction ProblemsScientific Centre for the Family Health and Human Reproduction ProblemsThe objective of this study was to identify features of the system of lipid peroxidation - antioxidant protection in 31 women of reproductive age with viral hepatitis A. In women with hepatitis A virus (HAV) (main group) there is an increase in the level of double bonds (31,1%) and active products reacting with thiobarbituric acid (141,7%) with a simultaneous decrease in the content of diene conjugates (69,4%), compared with the same indicators in the control group. The level of antioxidant protection in women in main group unlike the control was characterized by a decrease in total antioxidant activity (25,2%), by the inhibition of the activity of superoxide dismutase (29,1%), by decreasing the concentration of a-tocopherol (42,6%) on the background of increase of retinol level (184,6%). In general, the combination of prooxidant and antioxidant factors at HAV can be considered as a condition of oxidative stress (p < 0,05).https://www.actabiomedica.ru/jour/article/view/2viral hepatitis alipid peroxidation - antioxidant protection systemoxidative stresswomenreproductive age |
| spellingShingle | B. Ya. Vlasov M. A. Rashidova L. F. Sholokhov O. A. Vanteeva E. L. Chudinova Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A Acta Biomedica Scientifica viral hepatitis a lipid peroxidation - antioxidant protection system oxidative stress women reproductive age |
| title | Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A |
| title_full | Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A |
| title_fullStr | Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A |
| title_full_unstemmed | Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A |
| title_short | Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A |
| title_sort | status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis a |
| topic | viral hepatitis a lipid peroxidation - antioxidant protection system oxidative stress women reproductive age |
| url | https://www.actabiomedica.ru/jour/article/view/2 |
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