Ectopic Rod Photoreceptor Development in Mice with Genetic Deficiency of WNT2B

Ectopic Rod Photoreceptor Development in Mice with Genetic Deficiency of WNT2B

Wnt/β-catenin signaling is essential for embryonic eye development in both the anterior eye and retina. WNT2B, a ligand and activator of the Wnt/β-catenin pathway, assists in the development of the lens and peripheral regions of the eye. In humans <i>WNT2B</i> mutations are associated wi...

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Bibliographic Details
Main Authors: Alexandra K. Blomfield, Meenakshi Maurya, Kiran Bora, Madeline C. Pavlovich, Felix Yemanyi, Shuo Huang, Zhongjie Fu, Amy E. O’Connell, Jing Chen
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cells
Subjects:
Wnt signaling
WNT2B
photoreceptor
retina
development
Online Access:https://www.mdpi.com/2073-4409/12/7/1033

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