Rapid, High Affinity Binding by a Fluorescein Templated Copolymer Combining Covalent, Hydrophobic, and Acid–Base Noncovalent Crosslinks

Rapid, High Affinity Binding by a Fluorescein Templated Copolymer Combining Covalent, Hydrophobic, and Acid–Base Noncovalent Crosslinks

A new type of biomimetic templated copolymer has been prepared by reverse addition fragmentation chain transfer polymerization (RAFT) in dioxane. The initial formulation includes the template fluorescein, N-isopropylacrylamide (NIPAM, 84 mol %), methacrylic acid (MAA, 5-mol %), 4-vinylpyridine (4-VP...

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Bibliographic Details
Main Authors: Casey J. Grenier, Anthony Timberman, Rongfang Yang, John Csoros, Alex Papantones, Leila F. Deravi, W. Rudolf Seitz
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Sensors
Subjects:
templates
moleculary imprinted polymers
poly(N-isopropylacrylamide)
noncovalent crosslinks
fluorescein
binding affinity
binding kinetics
Online Access:http://www.mdpi.com/1424-8220/18/5/1330

Internet

http://www.mdpi.com/1424-8220/18/5/1330

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