Intraoperative cortical localization of music and language reveals signatures of structural complexity in posterior temporal cortex
Summary: Language and music involve the productive combination of basic units into structures. It remains unclear whether brain regions sensitive to linguistic and musical structure are co-localized. We report an intraoperative awake craniotomy in which a left-hemispheric language-dominant professio...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-07-01
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| Series: | iScience |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004223013007 |
| _version_ | 1797774514187141120 |
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| author | Meredith J. McCarty Elliot Murphy Xavier Scherschligt Oscar Woolnough Cale W. Morse Kathryn Snyder Bradford Z. Mahon Nitin Tandon |
| author_facet | Meredith J. McCarty Elliot Murphy Xavier Scherschligt Oscar Woolnough Cale W. Morse Kathryn Snyder Bradford Z. Mahon Nitin Tandon |
| author_sort | Meredith J. McCarty |
| collection | DOAJ |
| description | Summary: Language and music involve the productive combination of basic units into structures. It remains unclear whether brain regions sensitive to linguistic and musical structure are co-localized. We report an intraoperative awake craniotomy in which a left-hemispheric language-dominant professional musician underwent cortical stimulation mapping (CSM) and electrocorticography of music and language perception and production during repetition tasks. Musical sequences were melodic or amelodic, and differed in algorithmic compressibility (Lempel-Ziv complexity). Auditory recordings of sentences differed in syntactic complexity (single vs. multiple phrasal embeddings). CSM of posterior superior temporal gyrus (pSTG) disrupted music perception and production, along with speech production. pSTG and posterior middle temporal gyrus (pMTG) activated for language and music (broadband gamma; 70–150 Hz). pMTG activity was modulated by musical complexity, while pSTG activity was modulated by syntactic complexity. This points to shared resources for music and language comprehension, but distinct neural signatures for the processing of domain-specific structural features. |
| first_indexed | 2024-03-12T22:22:13Z |
| format | Article |
| id | doaj.art-e29ba2cb77914cdc9b1e797164aa7323 |
| institution | Directory Open Access Journal |
| issn | 2589-0042 |
| language | English |
| last_indexed | 2024-03-12T22:22:13Z |
| publishDate | 2023-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | iScience |
| spelling | doaj.art-e29ba2cb77914cdc9b1e797164aa73232023-07-23T04:55:59ZengElsevieriScience2589-00422023-07-01267107223Intraoperative cortical localization of music and language reveals signatures of structural complexity in posterior temporal cortexMeredith J. McCarty0Elliot Murphy1Xavier Scherschligt2Oscar Woolnough3Cale W. Morse4Kathryn Snyder5Bradford Z. Mahon6Nitin Tandon7Vivian L. Smith Department of Neurosurgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston, Houston, TX 77030, USAVivian L. Smith Department of Neurosurgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Corresponding authorVivian L. Smith Department of Neurosurgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston, Houston, TX 77030, USAVivian L. Smith Department of Neurosurgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston, Houston, TX 77030, USAVivian L. Smith Department of Neurosurgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston, Houston, TX 77030, USAVivian L. Smith Department of Neurosurgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston, Houston, TX 77030, USADepartment of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA 15213, USAVivian L. Smith Department of Neurosurgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Memorial Hermann Hospital, Texas Medical Center, Houston, TX 77030, USA; Corresponding authorSummary: Language and music involve the productive combination of basic units into structures. It remains unclear whether brain regions sensitive to linguistic and musical structure are co-localized. We report an intraoperative awake craniotomy in which a left-hemispheric language-dominant professional musician underwent cortical stimulation mapping (CSM) and electrocorticography of music and language perception and production during repetition tasks. Musical sequences were melodic or amelodic, and differed in algorithmic compressibility (Lempel-Ziv complexity). Auditory recordings of sentences differed in syntactic complexity (single vs. multiple phrasal embeddings). CSM of posterior superior temporal gyrus (pSTG) disrupted music perception and production, along with speech production. pSTG and posterior middle temporal gyrus (pMTG) activated for language and music (broadband gamma; 70–150 Hz). pMTG activity was modulated by musical complexity, while pSTG activity was modulated by syntactic complexity. This points to shared resources for music and language comprehension, but distinct neural signatures for the processing of domain-specific structural features.http://www.sciencedirect.com/science/article/pii/S2589004223013007Musical acousticsBiological sciencesNeuroscienceSensory neuroscience |
| spellingShingle | Meredith J. McCarty Elliot Murphy Xavier Scherschligt Oscar Woolnough Cale W. Morse Kathryn Snyder Bradford Z. Mahon Nitin Tandon Intraoperative cortical localization of music and language reveals signatures of structural complexity in posterior temporal cortex iScience Musical acoustics Biological sciences Neuroscience Sensory neuroscience |
| title | Intraoperative cortical localization of music and language reveals signatures of structural complexity in posterior temporal cortex |
| title_full | Intraoperative cortical localization of music and language reveals signatures of structural complexity in posterior temporal cortex |
| title_fullStr | Intraoperative cortical localization of music and language reveals signatures of structural complexity in posterior temporal cortex |
| title_full_unstemmed | Intraoperative cortical localization of music and language reveals signatures of structural complexity in posterior temporal cortex |
| title_short | Intraoperative cortical localization of music and language reveals signatures of structural complexity in posterior temporal cortex |
| title_sort | intraoperative cortical localization of music and language reveals signatures of structural complexity in posterior temporal cortex |
| topic | Musical acoustics Biological sciences Neuroscience Sensory neuroscience |
| url | http://www.sciencedirect.com/science/article/pii/S2589004223013007 |
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