Enhanced structural stability of DNA origami nanostructures by graphene encapsulation
We demonstrate that a single-layer graphene replicates the shape of DNA origami nanostructures very well. It can be employed as a protective layer for the enhancement of structural stability of DNA origami nanostructures. Using the AFM based manipulation, we show that the normal force required to da...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
IOP Publishing
2016-01-01
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| Series: | New Journal of Physics |
| Subjects: | |
| Online Access: | https://doi.org/10.1088/1367-2630/18/2/025016 |
| _version_ | 1797751061479424000 |
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| author | Aleksandar Matković Borislav Vasić Jelena Pešić Julia Prinz Ilko Bald Aleksandar R Milosavljević Radoš Gajić |
| author_facet | Aleksandar Matković Borislav Vasić Jelena Pešić Julia Prinz Ilko Bald Aleksandar R Milosavljević Radoš Gajić |
| author_sort | Aleksandar Matković |
| collection | DOAJ |
| description | We demonstrate that a single-layer graphene replicates the shape of DNA origami nanostructures very well. It can be employed as a protective layer for the enhancement of structural stability of DNA origami nanostructures. Using the AFM based manipulation, we show that the normal force required to damage graphene encapsulated DNA origami nanostructures is over an order of magnitude greater than for the unprotected ones. In addition, we show that graphene encapsulation offers protection to the DNA origami nanostructures against prolonged exposure to deionized water, and multiple immersions. Through these results we demonstrate that graphene encapsulated DNA origami nanostructures are strong enough to sustain various solution phase processing, lithography and transfer steps, thus extending the limits of DNA-mediated bottom-up fabrication. |
| first_indexed | 2024-03-12T16:41:55Z |
| format | Article |
| id | doaj.art-e29cc4da2bae45b9a100529d2b722611 |
| institution | Directory Open Access Journal |
| issn | 1367-2630 |
| language | English |
| last_indexed | 2024-03-12T16:41:55Z |
| publishDate | 2016-01-01 |
| publisher | IOP Publishing |
| record_format | Article |
| series | New Journal of Physics |
| spelling | doaj.art-e29cc4da2bae45b9a100529d2b7226112023-08-08T14:27:37ZengIOP PublishingNew Journal of Physics1367-26302016-01-0118202501610.1088/1367-2630/18/2/025016Enhanced structural stability of DNA origami nanostructures by graphene encapsulationAleksandar Matković0Borislav Vasić1Jelena Pešić2Julia Prinz3Ilko Bald4Aleksandar R Milosavljević5Radoš Gajić6Center for Solid State Physics and New Materials, Institute of Physics, University of Belgrade , Pregrevica 118, 11080 Belgrade, Serbia; Present address: Institute of Physics, Montanuniversität Leoben, Franz Josef Straße 18, A-8700 Leoben, AustriaCenter for Solid State Physics and New Materials, Institute of Physics, University of Belgrade , Pregrevica 118, 11080 Belgrade, SerbiaCenter for Solid State Physics and New Materials, Institute of Physics, University of Belgrade , Pregrevica 118, 11080 Belgrade, SerbiaInstitute of Chemistry—Physical Chemistry, University of Potsdam , Potsdam, GermanyInstitute of Chemistry—Physical Chemistry, University of Potsdam , Potsdam, Germany; BAM Federal Institute for Materials Research and Testing, Richard-Willsttter Str. 11, D-12489 Berlin, GermanyLaboratory for Atomic Collision Processes, Institute of Physics, University of Belgrade , Pregrevica 118, 11080 Belgrade, Serbia; Present address: Radiation Laboratory, University of Notre Dame, Notre Dame, IN 46556, USACenter for Solid State Physics and New Materials, Institute of Physics, University of Belgrade , Pregrevica 118, 11080 Belgrade, SerbiaWe demonstrate that a single-layer graphene replicates the shape of DNA origami nanostructures very well. It can be employed as a protective layer for the enhancement of structural stability of DNA origami nanostructures. Using the AFM based manipulation, we show that the normal force required to damage graphene encapsulated DNA origami nanostructures is over an order of magnitude greater than for the unprotected ones. In addition, we show that graphene encapsulation offers protection to the DNA origami nanostructures against prolonged exposure to deionized water, and multiple immersions. Through these results we demonstrate that graphene encapsulated DNA origami nanostructures are strong enough to sustain various solution phase processing, lithography and transfer steps, thus extending the limits of DNA-mediated bottom-up fabrication.https://doi.org/10.1088/1367-2630/18/2/025016grapheneDNA origami nanostructuresatomic force microscopy |
| spellingShingle | Aleksandar Matković Borislav Vasić Jelena Pešić Julia Prinz Ilko Bald Aleksandar R Milosavljević Radoš Gajić Enhanced structural stability of DNA origami nanostructures by graphene encapsulation New Journal of Physics graphene DNA origami nanostructures atomic force microscopy |
| title | Enhanced structural stability of DNA origami nanostructures by graphene encapsulation |
| title_full | Enhanced structural stability of DNA origami nanostructures by graphene encapsulation |
| title_fullStr | Enhanced structural stability of DNA origami nanostructures by graphene encapsulation |
| title_full_unstemmed | Enhanced structural stability of DNA origami nanostructures by graphene encapsulation |
| title_short | Enhanced structural stability of DNA origami nanostructures by graphene encapsulation |
| title_sort | enhanced structural stability of dna origami nanostructures by graphene encapsulation |
| topic | graphene DNA origami nanostructures atomic force microscopy |
| url | https://doi.org/10.1088/1367-2630/18/2/025016 |
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