Real‐world trends in pre‐dialysis blood pressure levels of patients undergoing dialysis in Japan using a web‐based national database
Abstract The prevalence of hypertension is high among patients undergoing dialysis. We extracted data of patients undergoing dialysis between 2012 and 2020 with recorded pre‐dialysis systolic blood pressure (SBP) using a web‐based national database in Japan. Following the 2019 Japanese Society of Hy...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-12-01
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| Series: | The Journal of Clinical Hypertension |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/jch.14736 |
| _version_ | 1797398384281124864 |
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| author | Hirofumi Sakuma Motoki Matsuki Naoyuki Hasebe Naoki Nakagawa |
| author_facet | Hirofumi Sakuma Motoki Matsuki Naoyuki Hasebe Naoki Nakagawa |
| author_sort | Hirofumi Sakuma |
| collection | DOAJ |
| description | Abstract The prevalence of hypertension is high among patients undergoing dialysis. We extracted data of patients undergoing dialysis between 2012 and 2020 with recorded pre‐dialysis systolic blood pressure (SBP) using a web‐based national database in Japan. Following the 2019 Japanese Society of Hypertension guidelines, we classified SBP and assessed its trends over time based on sex, age, diabetes status, and the anti‐hypertensive medication use. Using the 2020 database, we examined 336,759 Japanese patients undergoing dialysis (114,249 female; 222,510 male). The mean age was 69.4 ± 12.5 years, and the mean SBP was 152.3 ± 24.7 mm Hg. The prevalence rate of pre‐dialysis hypertension was 70.2%, with 32.5%, 24.5%, and 13.2% of patients having grade I, grade II, and grade III hypertension, respectively. From 2014 to 2020, prevalence rate of pre‐dialysis hypertension and absolute values of pre‐dialysis SBP were higher in dialysis patients with diabetes than in those without diabetes across all age groups and sexes. Younger patients with diabetes or those on anti‐hypertensive medication exhibited an SBP of approximately 160 mm Hg. Cerebrovascular death in patients with diabetes was associated with a higher rate of pre‐dialysis hypertension than that in those without diabetes, and there was a significant difference in the prevalence of grade III hypertension between the two groups. In conclusion, the mean pre‐dialysis SBP among patients undergoing dialysis remained high, and younger patients with diabetes or those receiving anti‐hypertensive medications had poor blood pressure control. Optimal blood pressure management may be necessary to reduce the risk of cardiovascular mortality. |
| first_indexed | 2024-03-09T01:24:53Z |
| format | Article |
| id | doaj.art-e2a3a98f08a6469eaffa8e30495a2c5e |
| institution | Directory Open Access Journal |
| issn | 1524-6175 1751-7176 |
| language | English |
| last_indexed | 2024-03-09T01:24:53Z |
| publishDate | 2023-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Journal of Clinical Hypertension |
| spelling | doaj.art-e2a3a98f08a6469eaffa8e30495a2c5e2023-12-10T07:14:34ZengWileyThe Journal of Clinical Hypertension1524-61751751-71762023-12-0125121163117110.1111/jch.14736Real‐world trends in pre‐dialysis blood pressure levels of patients undergoing dialysis in Japan using a web‐based national databaseHirofumi Sakuma0Motoki Matsuki1Naoyuki Hasebe2Naoki Nakagawa3Division of Cardiology, Nephrology, Respiratory, and Neurology, Department of Internal Medicine Asahikawa Medical University Asahikawa Hokkaido JapanDivision of Cardiology, Nephrology, Respiratory, and Neurology, Department of Internal Medicine Asahikawa Medical University Asahikawa Hokkaido JapanDivision of Cardiology, Nephrology, Respiratory, and Neurology, Department of Internal Medicine Asahikawa Medical University Asahikawa Hokkaido JapanDivision of Cardiology, Nephrology, Respiratory, and Neurology, Department of Internal Medicine Asahikawa Medical University Asahikawa Hokkaido JapanAbstract The prevalence of hypertension is high among patients undergoing dialysis. We extracted data of patients undergoing dialysis between 2012 and 2020 with recorded pre‐dialysis systolic blood pressure (SBP) using a web‐based national database in Japan. Following the 2019 Japanese Society of Hypertension guidelines, we classified SBP and assessed its trends over time based on sex, age, diabetes status, and the anti‐hypertensive medication use. Using the 2020 database, we examined 336,759 Japanese patients undergoing dialysis (114,249 female; 222,510 male). The mean age was 69.4 ± 12.5 years, and the mean SBP was 152.3 ± 24.7 mm Hg. The prevalence rate of pre‐dialysis hypertension was 70.2%, with 32.5%, 24.5%, and 13.2% of patients having grade I, grade II, and grade III hypertension, respectively. From 2014 to 2020, prevalence rate of pre‐dialysis hypertension and absolute values of pre‐dialysis SBP were higher in dialysis patients with diabetes than in those without diabetes across all age groups and sexes. Younger patients with diabetes or those on anti‐hypertensive medication exhibited an SBP of approximately 160 mm Hg. Cerebrovascular death in patients with diabetes was associated with a higher rate of pre‐dialysis hypertension than that in those without diabetes, and there was a significant difference in the prevalence of grade III hypertension between the two groups. In conclusion, the mean pre‐dialysis SBP among patients undergoing dialysis remained high, and younger patients with diabetes or those receiving anti‐hypertensive medications had poor blood pressure control. Optimal blood pressure management may be necessary to reduce the risk of cardiovascular mortality.https://doi.org/10.1111/jch.14736dialysispre‐dialysis hypertensionregistry |
| spellingShingle | Hirofumi Sakuma Motoki Matsuki Naoyuki Hasebe Naoki Nakagawa Real‐world trends in pre‐dialysis blood pressure levels of patients undergoing dialysis in Japan using a web‐based national database The Journal of Clinical Hypertension dialysis pre‐dialysis hypertension registry |
| title | Real‐world trends in pre‐dialysis blood pressure levels of patients undergoing dialysis in Japan using a web‐based national database |
| title_full | Real‐world trends in pre‐dialysis blood pressure levels of patients undergoing dialysis in Japan using a web‐based national database |
| title_fullStr | Real‐world trends in pre‐dialysis blood pressure levels of patients undergoing dialysis in Japan using a web‐based national database |
| title_full_unstemmed | Real‐world trends in pre‐dialysis blood pressure levels of patients undergoing dialysis in Japan using a web‐based national database |
| title_short | Real‐world trends in pre‐dialysis blood pressure levels of patients undergoing dialysis in Japan using a web‐based national database |
| title_sort | real world trends in pre dialysis blood pressure levels of patients undergoing dialysis in japan using a web based national database |
| topic | dialysis pre‐dialysis hypertension registry |
| url | https://doi.org/10.1111/jch.14736 |
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