Human CD206+ macrophages associate with diabetes and adipose tissue lymphoid clusters

Human CD206+ macrophages associate with diabetes and adipose tissue lymphoid clusters

Increased adipose tissue macrophages (ATMs) correlate with metabolic dysfunction in humans and are causal in development of insulin resistance in mice. Recent bulk and single-cell transcriptomics studies reveal a wide spectrum of gene expression signatures possible for macrophages that depends on co...

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Bibliographic Details
Main Authors: Lindsey A. Muir, Kae Won Cho, Lynn M. Geletka, Nicki A. Baker, Carmen G. Flesher, Anne P. Ehlers, Niko Kaciroti, Stephen Lindsly, Scott Ronquist, Indika Rajapakse, Robert W. O’Rourke, Carey N. Lumeng
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-02-01
Series:JCI Insight
Subjects:
Immunology
Metabolism
Online Access:https://doi.org/10.1172/jci.insight.146563

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