Robotic-Assisted vs. Open Simple Prostatectomy for Large Prostates: A Meta-Analysis
Purpose: To compare the efficacy and safety of robotic-assisted simple prostatectomy and open simple prostatectomy for large benign prostatic hyperplasia.Methods: We systematically searched the Cochrane Library, PubMed, Embase, and Science databases for studies published through December 2020. Contr...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-07-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2021.695318/full |
| _version_ | 1819144444286337024 |
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| author | Zhongyou Xia Jinze Li Jinze Li Xiaoying Yang Hao Jing Chao Niu Xianhui Li Yunxiang Li Zongping Zhang Ji Wu |
| author_facet | Zhongyou Xia Jinze Li Jinze Li Xiaoying Yang Hao Jing Chao Niu Xianhui Li Yunxiang Li Zongping Zhang Ji Wu |
| author_sort | Zhongyou Xia |
| collection | DOAJ |
| description | Purpose: To compare the efficacy and safety of robotic-assisted simple prostatectomy and open simple prostatectomy for large benign prostatic hyperplasia.Methods: We systematically searched the Cochrane Library, PubMed, Embase, and Science databases for studies published through December 2020. Controlled trials on RASP and OSP for large prostates were included. The meta-analysis was conducted with the Review Manager 5.4 software.Results: A total of seven studies with 3,777 patients were included in the analysis. There were no significant differences in IPSS (WMD, 0.72; 95%CI: −0.31, 1.76; P = 0.17), QoL (WMD, 0.00; 95%CI: −0.39, 0.39; P > 0.99), Qmax (WMD, 1.88; 95% CI: −1.15, 4.91; P = 0.22), or PVR (WMD, −10.48; 95%CI: −25.13, 4.17; P = 0.16) among patients undergoing RASP and OSP. However, compared with patients who underwent OSP, patients who underwent RASP had a shorter LOS (WMD, −2.83; 95%CI: −3.68, −1.98; P < 0.001), less EBL (WMD, −304.68; 95% CI: −432.91, −176.44; P < 0.001), a shorter CT (WMD, −2.61; 95%CI: −3.94, −1.29; P < 0.001), and fewer overall complications (OR, 0.30; 95% CI: 0.16, 0.57; P < 0.001). Nevertheless, RASP was associated with a longer OT (WMD, 59.69, 95% CI: 49.40, 69.98; P < 0.001).Conclusion: The results of the current study demonstrated that RASP provided similar efficacy to those of OSP in the treatment of large prostate, while maintaining better security. Our findings indicate that RASP is a feasible and effective alternative to OSP. |
| first_indexed | 2024-12-22T12:42:14Z |
| format | Article |
| id | doaj.art-e2a70dbc0b6d4109999caa091f1862c3 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-12-22T12:42:14Z |
| publishDate | 2021-07-01 |
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| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-e2a70dbc0b6d4109999caa091f1862c32022-12-21T18:25:24ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2021-07-01810.3389/fsurg.2021.695318695318Robotic-Assisted vs. Open Simple Prostatectomy for Large Prostates: A Meta-AnalysisZhongyou Xia0Jinze Li1Jinze Li2Xiaoying Yang3Hao Jing4Chao Niu5Xianhui Li6Yunxiang Li7Zongping Zhang8Ji Wu9Department of Urology, Nanchong Central Hospital, The Second Clinical College, North Sichuan Medical College, Nanchong, ChinaDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, ChinaWest China School of Medicine, Sichuan University, Chengdu, ChinaBlood Purification Center of Department of Nephrology, Nanchong Central Hospital, The Second Clinical College, North Sichuan Medical College, Nanchong, ChinaDepartment of Urology, Pidu District People's Hospital, Chengdu, ChinaDepartment of Urology, Nanchong Central Hospital, The Second Clinical College, North Sichuan Medical College, Nanchong, ChinaDepartment of Urology, Nanchong Central Hospital, The Second Clinical College, North Sichuan Medical College, Nanchong, ChinaDepartment of Urology, Nanchong Central Hospital, The Second Clinical College, North Sichuan Medical College, Nanchong, ChinaDepartment of Urology, Nanchong Central Hospital, The Second Clinical College, North Sichuan Medical College, Nanchong, ChinaDepartment of Urology, Nanchong Central Hospital, The Second Clinical College, North Sichuan Medical College, Nanchong, ChinaPurpose: To compare the efficacy and safety of robotic-assisted simple prostatectomy and open simple prostatectomy for large benign prostatic hyperplasia.Methods: We systematically searched the Cochrane Library, PubMed, Embase, and Science databases for studies published through December 2020. Controlled trials on RASP and OSP for large prostates were included. The meta-analysis was conducted with the Review Manager 5.4 software.Results: A total of seven studies with 3,777 patients were included in the analysis. There were no significant differences in IPSS (WMD, 0.72; 95%CI: −0.31, 1.76; P = 0.17), QoL (WMD, 0.00; 95%CI: −0.39, 0.39; P > 0.99), Qmax (WMD, 1.88; 95% CI: −1.15, 4.91; P = 0.22), or PVR (WMD, −10.48; 95%CI: −25.13, 4.17; P = 0.16) among patients undergoing RASP and OSP. However, compared with patients who underwent OSP, patients who underwent RASP had a shorter LOS (WMD, −2.83; 95%CI: −3.68, −1.98; P < 0.001), less EBL (WMD, −304.68; 95% CI: −432.91, −176.44; P < 0.001), a shorter CT (WMD, −2.61; 95%CI: −3.94, −1.29; P < 0.001), and fewer overall complications (OR, 0.30; 95% CI: 0.16, 0.57; P < 0.001). Nevertheless, RASP was associated with a longer OT (WMD, 59.69, 95% CI: 49.40, 69.98; P < 0.001).Conclusion: The results of the current study demonstrated that RASP provided similar efficacy to those of OSP in the treatment of large prostate, while maintaining better security. Our findings indicate that RASP is a feasible and effective alternative to OSP.https://www.frontiersin.org/articles/10.3389/fsurg.2021.695318/fullbenign prostatic hyperplasiasimple prostatectomyroboticopenmeta-analysis |
| spellingShingle | Zhongyou Xia Jinze Li Jinze Li Xiaoying Yang Hao Jing Chao Niu Xianhui Li Yunxiang Li Zongping Zhang Ji Wu Robotic-Assisted vs. Open Simple Prostatectomy for Large Prostates: A Meta-Analysis Frontiers in Surgery benign prostatic hyperplasia simple prostatectomy robotic open meta-analysis |
| title | Robotic-Assisted vs. Open Simple Prostatectomy for Large Prostates: A Meta-Analysis |
| title_full | Robotic-Assisted vs. Open Simple Prostatectomy for Large Prostates: A Meta-Analysis |
| title_fullStr | Robotic-Assisted vs. Open Simple Prostatectomy for Large Prostates: A Meta-Analysis |
| title_full_unstemmed | Robotic-Assisted vs. Open Simple Prostatectomy for Large Prostates: A Meta-Analysis |
| title_short | Robotic-Assisted vs. Open Simple Prostatectomy for Large Prostates: A Meta-Analysis |
| title_sort | robotic assisted vs open simple prostatectomy for large prostates a meta analysis |
| topic | benign prostatic hyperplasia simple prostatectomy robotic open meta-analysis |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2021.695318/full |
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