Antidiabetic and Antioxidant Properties of Sea Urchin Echinometra mathaei from the Persian Gulf
Background: The aim of the present study was to evaluate the inhibition of α-glucosidase and antioxidant properties of different tissues of sea urchin Echinometra mathaei. Methods: α-glucosidase inhibition was determined using p-Nitrophenyl-a-D-glucopyranoside as a substrate, and the antioxidant pro...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Kerman University of Medical Sciences
2021-01-01
|
| Series: | Journal of Kerman University of Medical Sciences |
| Subjects: | |
| Online Access: | https://jkmu.kmu.ac.ir/article_91569_e7512c883b8f508282e5d75d0cddb487.pdf |
| _version_ | 1797790791495581696 |
|---|---|
| author | Soolmaz Soleimani Elham Pirmoradloo Fatemeh Farmani Soheila Moein Morteza Yousefzadi |
| author_facet | Soolmaz Soleimani Elham Pirmoradloo Fatemeh Farmani Soheila Moein Morteza Yousefzadi |
| author_sort | Soolmaz Soleimani |
| collection | DOAJ |
| description | Background: The aim of the present study was to evaluate the inhibition of α-glucosidase and antioxidant properties of different tissues of sea urchin Echinometra mathaei. Methods: α-glucosidase inhibition was determined using p-Nitrophenyl-a-D-glucopyranoside as a substrate, and the antioxidant properties were evaluated by 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS),1,1-diphenyl-2-picrylhydrazyl (DPPH), and nitric oxide radicals scavenging. Also, antioxidant potential was evaluated by the ferric reducing antioxidant power (FRAP) method. Results: Among the studied tissues, the highest α-glucosidase inhibition was revealed by the ethyl acetate extract of the shell and Aristotle’s lantern (IC50 = 3.7 and 4 mg/mL, respectively). Shell had the highest ABTS (IC50 = 183) and DPPH (IC50 = 208 μg/mL) radicals scavenging, respectively. And, gonad had the highest antioxidant potential by the FRAP method (1140 μg ASA/mg) and NO radical scavenging (70.68%), respectively. Conclusion: Antidiabetic potentials of the ethyl acetate extracts of sea urchin tissues suggest that these extracts can be used as antidiabetic drugs. |
| first_indexed | 2024-03-13T02:09:33Z |
| format | Article |
| id | doaj.art-e2a7c348e2454d5a8f59ca6c236b0b64 |
| institution | Directory Open Access Journal |
| issn | 2008-2843 |
| language | English |
| last_indexed | 2024-03-13T02:09:33Z |
| publishDate | 2021-01-01 |
| publisher | Kerman University of Medical Sciences |
| record_format | Article |
| series | Journal of Kerman University of Medical Sciences |
| spelling | doaj.art-e2a7c348e2454d5a8f59ca6c236b0b642023-07-01T05:11:19ZengKerman University of Medical SciencesJournal of Kerman University of Medical Sciences2008-28432021-01-0128110411510.22062/jkmu.2021.9156991569Antidiabetic and Antioxidant Properties of Sea Urchin Echinometra mathaei from the Persian GulfSoolmaz Soleimani0Elham Pirmoradloo1Fatemeh Farmani2Soheila Moein3Morteza Yousefzadi4Professor of Department of Marine Biology, Faculty of Marine Science and Technology, University of Hormozgan, Bandar Abbas, IranDepartment of Biochemistry, Fars Sciences and Research Branch, Islamic Azad University, Shiraz, IranMedicinal Plants Processing Research Center, Shiraz University of Medical Sciences, Shiraz, IranProfessor of Medicinal Plants Processing Research Center, Shiraz University of Medical Sciences, Shiraz, IranProfessor of Department of Marine Biology, Faculty of Marine Science and Technology, University of Hormozgan, Bandar Abbas, IranBackground: The aim of the present study was to evaluate the inhibition of α-glucosidase and antioxidant properties of different tissues of sea urchin Echinometra mathaei. Methods: α-glucosidase inhibition was determined using p-Nitrophenyl-a-D-glucopyranoside as a substrate, and the antioxidant properties were evaluated by 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS),1,1-diphenyl-2-picrylhydrazyl (DPPH), and nitric oxide radicals scavenging. Also, antioxidant potential was evaluated by the ferric reducing antioxidant power (FRAP) method. Results: Among the studied tissues, the highest α-glucosidase inhibition was revealed by the ethyl acetate extract of the shell and Aristotle’s lantern (IC50 = 3.7 and 4 mg/mL, respectively). Shell had the highest ABTS (IC50 = 183) and DPPH (IC50 = 208 μg/mL) radicals scavenging, respectively. And, gonad had the highest antioxidant potential by the FRAP method (1140 μg ASA/mg) and NO radical scavenging (70.68%), respectively. Conclusion: Antidiabetic potentials of the ethyl acetate extracts of sea urchin tissues suggest that these extracts can be used as antidiabetic drugs.https://jkmu.kmu.ac.ir/article_91569_e7512c883b8f508282e5d75d0cddb487.pdfantidiabeticantioxidant properties echinometra mathaei the persian gulf |
| spellingShingle | Soolmaz Soleimani Elham Pirmoradloo Fatemeh Farmani Soheila Moein Morteza Yousefzadi Antidiabetic and Antioxidant Properties of Sea Urchin Echinometra mathaei from the Persian Gulf Journal of Kerman University of Medical Sciences antidiabetic antioxidant properties echinometra mathaei the persian gulf |
| title | Antidiabetic and Antioxidant Properties of Sea Urchin Echinometra mathaei from the Persian Gulf |
| title_full | Antidiabetic and Antioxidant Properties of Sea Urchin Echinometra mathaei from the Persian Gulf |
| title_fullStr | Antidiabetic and Antioxidant Properties of Sea Urchin Echinometra mathaei from the Persian Gulf |
| title_full_unstemmed | Antidiabetic and Antioxidant Properties of Sea Urchin Echinometra mathaei from the Persian Gulf |
| title_short | Antidiabetic and Antioxidant Properties of Sea Urchin Echinometra mathaei from the Persian Gulf |
| title_sort | antidiabetic and antioxidant properties of sea urchin echinometra mathaei from the persian gulf |
| topic | antidiabetic antioxidant properties echinometra mathaei the persian gulf |
| url | https://jkmu.kmu.ac.ir/article_91569_e7512c883b8f508282e5d75d0cddb487.pdf |
| work_keys_str_mv | AT soolmazsoleimani antidiabeticandantioxidantpropertiesofseaurchinechinometramathaeifromthepersiangulf AT elhampirmoradloo antidiabeticandantioxidantpropertiesofseaurchinechinometramathaeifromthepersiangulf AT fatemehfarmani antidiabeticandantioxidantpropertiesofseaurchinechinometramathaeifromthepersiangulf AT soheilamoein antidiabeticandantioxidantpropertiesofseaurchinechinometramathaeifromthepersiangulf AT mortezayousefzadi antidiabeticandantioxidantpropertiesofseaurchinechinometramathaeifromthepersiangulf |