Multiple Treg suppressive modules and their adaptability

Foxp3+ regulatory T-cells (Tregs) are a constitutively immunosuppressive cell type critical for the control of autoimmunity and inflammatory pathology. A range of mechanisms of Treg suppression have been identified and it has not always been clear how these different mechanisms interact in order to...

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Bibliographic Details
Main Authors: James Badger Wing, Shimon eSakaguchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00178/full

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