Multiple Treg suppressive modules and their adaptability
Foxp3+ regulatory T-cells (Tregs) are a constitutively immunosuppressive cell type critical for the control of autoimmunity and inflammatory pathology. A range of mechanisms of Treg suppression have been identified and it has not always been clear how these different mechanisms interact in order to...
Main Authors: | James Badger Wing, Shimon eSakaguchi |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-06-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00178/full |
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