Toxicological safety evaluation of Qin-Zhi-Zhu-Dan formula in rats during the treatment and recovery periods

Toxicological safety evaluation of Qin-Zhi-Zhu-Dan formula in rats during the treatment and recovery periods

Background: Qinzhi Zhudan Formula (QZZD), optimized from Angong Niuhuang Wan, consists of Radix Scutellariae, Fructus Gardeniae and Pulvis Fellis Suis. We had investigated the neuroprotective effects of QZZD and its active components, and demonstrated that it could treat cerebral ischemia and dement...

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Bibliographic Details
Main Authors: Wenxiu Xu, Dan Chen, Zehan Zhang, Shuling Liu, Congai Chen, Chunyan Sun, Wenchao Ni, Xiangdong Kang, Guojiao Shang, Xueqian Wang, Fafeng Cheng, Qingguo Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
sub-chronic toxicity
scutellaria baicalensis extract
gardenia extract
pulvis fellis suis
reversibility study
organ coefficient
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.987997/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.987997/full

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