Irrational ophthalmic fixed-dose combinations for dry eye syndrome

Dry eye syndrome (DES) is a common disorder with rising incidence due to increased use of digital devices. While multiple treatment options are available, some are not efficacious or sometimes even safe for use in DES. This is particularly true for Fixed Dose Combinations (FDCs) that may contain ing...

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Main Authors: Nilima A Kshirsagar, Renuka Munshi, Sandeep B Bavdekar, Rohit Saxena
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=10;spage=3687;epage=3689;aulast=Kshirsagar
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author Nilima A Kshirsagar
Renuka Munshi
Sandeep B Bavdekar
Rohit Saxena
author_facet Nilima A Kshirsagar
Renuka Munshi
Sandeep B Bavdekar
Rohit Saxena
author_sort Nilima A Kshirsagar
collection DOAJ
description Dry eye syndrome (DES) is a common disorder with rising incidence due to increased use of digital devices. While multiple treatment options are available, some are not efficacious or sometimes even safe for use in DES. This is particularly true for Fixed Dose Combinations (FDCs) that may contain ingredients having no rational for their use or may actually be harmful. Various committees appointed by the Government have reviewed several FDCs marketed in India and found some of them to be irrational and recommended for their removal. This paper discusses the contents of some of these FDCs marketed for DES with an aim to ensure that prescribers are mindful of their ingredients and whether there is adequate data about their efficacy and safety and prescribe them only if they consider them necessary for managing the patient.
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spelling doaj.art-e2ac77228e1a445489db08f63dfbf4f22022-12-22T03:32:10ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892022-01-0170103687368910.4103/ijo.IJO_1169_22Irrational ophthalmic fixed-dose combinations for dry eye syndromeNilima A KshirsagarRenuka MunshiSandeep B BavdekarRohit SaxenaDry eye syndrome (DES) is a common disorder with rising incidence due to increased use of digital devices. While multiple treatment options are available, some are not efficacious or sometimes even safe for use in DES. This is particularly true for Fixed Dose Combinations (FDCs) that may contain ingredients having no rational for their use or may actually be harmful. Various committees appointed by the Government have reviewed several FDCs marketed in India and found some of them to be irrational and recommended for their removal. This paper discusses the contents of some of these FDCs marketed for DES with an aim to ensure that prescribers are mindful of their ingredients and whether there is adequate data about their efficacy and safety and prescribe them only if they consider them necessary for managing the patient.http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=10;spage=3687;epage=3689;aulast=Kshirsagarfixed-dose combinationsfdcsdrug technical advisory board [dtab]dry eyeeyedropsirrational ophthalmic drops
spellingShingle Nilima A Kshirsagar
Renuka Munshi
Sandeep B Bavdekar
Rohit Saxena
Irrational ophthalmic fixed-dose combinations for dry eye syndrome
Indian Journal of Ophthalmology
fixed-dose combinations
fdcs
drug technical advisory board [dtab]
dry eye
eyedrops
irrational ophthalmic drops
title Irrational ophthalmic fixed-dose combinations for dry eye syndrome
title_full Irrational ophthalmic fixed-dose combinations for dry eye syndrome
title_fullStr Irrational ophthalmic fixed-dose combinations for dry eye syndrome
title_full_unstemmed Irrational ophthalmic fixed-dose combinations for dry eye syndrome
title_short Irrational ophthalmic fixed-dose combinations for dry eye syndrome
title_sort irrational ophthalmic fixed dose combinations for dry eye syndrome
topic fixed-dose combinations
fdcs
drug technical advisory board [dtab]
dry eye
eyedrops
irrational ophthalmic drops
url http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=10;spage=3687;epage=3689;aulast=Kshirsagar
work_keys_str_mv AT nilimaakshirsagar irrationalophthalmicfixeddosecombinationsfordryeyesyndrome
AT renukamunshi irrationalophthalmicfixeddosecombinationsfordryeyesyndrome
AT sandeepbbavdekar irrationalophthalmicfixeddosecombinationsfordryeyesyndrome
AT rohitsaxena irrationalophthalmicfixeddosecombinationsfordryeyesyndrome