A 35-bp Conserved Region Is Crucial for <i>Insl3</i> Promoter Activity in Mouse MA-10 Leydig Cells

A 35-bp Conserved Region Is Crucial for <i>Insl3</i> Promoter Activity in Mouse MA-10 Leydig Cells

The peptide hormone insulin-like 3 (INSL3) is produced almost exclusively by Leydig cells of the male gonad. INSL3 has several functions such as fetal testis descent and bone metabolism in adults. <i>Insl3</i> gene expression in Leydig cells is not hormonally regulated but rather is cons...

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Bibliographic Details
Main Authors: Xavier C. Giner, Kenley Joule Pierre, Nicholas M. Robert, Jacques J. Tremblay
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
Leydig cells
insulin-like 3
transcription
transcription factors
linker-scanning mutagenesis
DNA–protein interactions
Online Access:https://www.mdpi.com/1422-0067/23/23/15060

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