A Short-Term Intervention of High-Intensity Exercise and Anodal-tDCS on Motor Learning in Middle-Aged Adults: An RCT
High-intensity exercise has enhanced motor learning in healthy young adults. Anodal-transcranial direct current stimulation (a-tDCS) may optimize these effects. This study aimed to determine the effects of a short-term high-intensity interval exercise intervention either with or without a-tDCS on th...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2021-06-01
|
| Series: | Frontiers in Human Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnhum.2021.661079/full |
| _version_ | 1818457873234001920 |
|---|---|
| author | Clare Quinlan Clare Quinlan Ben Rattray Ben Rattray Ben Rattray Disa Pryor Joseph M. Northey Joseph M. Northey Joseph M. Northey James Coxon Nicolas Cherbuin Sophie C. Andrews Sophie C. Andrews Sophie C. Andrews Sophie C. Andrews |
| author_facet | Clare Quinlan Clare Quinlan Ben Rattray Ben Rattray Ben Rattray Disa Pryor Joseph M. Northey Joseph M. Northey Joseph M. Northey James Coxon Nicolas Cherbuin Sophie C. Andrews Sophie C. Andrews Sophie C. Andrews Sophie C. Andrews |
| author_sort | Clare Quinlan |
| collection | DOAJ |
| description | High-intensity exercise has enhanced motor learning in healthy young adults. Anodal-transcranial direct current stimulation (a-tDCS) may optimize these effects. This study aimed to determine the effects of a short-term high-intensity interval exercise intervention either with or without a-tDCS on the learning and retention of a novel motor task in middle-aged adults. Forty-two healthy middle-aged adults (age = 44.6 ± 6.3, female = 76%) were randomized into three groups: exercise and active a-tDCS, exercise and sham a-tDCS, and a non-exercise and sham a-tDCS control. Participants completed a baseline testing session, followed by three intervention sessions 48-h apart. The exercise groups completed 20-min of high-intensity exercise followed by a novel sequential visual isometric pinch task (SVIPT) while receiving 20-min of 1.5 mA a-tDCS, or sham tDCS. The control group completed 20-min of reading before receiving sham a-tDCS during the SVIPT. Learning was assessed by skill change within and between intervention sessions. Participants returned 5–7 days after the final intervention session and performed the SVIPT task to assess retention. All three groups showed evidence of learning on the SVIPT task. Neither group displayed enhanced overall learning or retention when compared to the control group. High-intensity exercise with or without a-tDCS did not improve learning or retention of a novel motor task in middle-aged adults. The methodological framework provides direction for future research to investigate the potential of differing exercise intensity effects on learning and retention. |
| first_indexed | 2024-12-14T22:49:29Z |
| format | Article |
| id | doaj.art-e2c2c47ab5c9433da4430cb006badf87 |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-12-14T22:49:29Z |
| publishDate | 2021-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-e2c2c47ab5c9433da4430cb006badf872022-12-21T22:44:46ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612021-06-011510.3389/fnhum.2021.661079661079A Short-Term Intervention of High-Intensity Exercise and Anodal-tDCS on Motor Learning in Middle-Aged Adults: An RCTClare Quinlan0Clare Quinlan1Ben Rattray2Ben Rattray3Ben Rattray4Disa Pryor5Joseph M. Northey6Joseph M. Northey7Joseph M. Northey8James Coxon9Nicolas Cherbuin10Sophie C. Andrews11Sophie C. Andrews12Sophie C. Andrews13Sophie C. Andrews14UC Research Institute for Sport and Exercise, University of Canberra, Canberra, ACT, AustraliaDiscipline of Sport and Exercise Science, Faculty of Health, University of Canberra, Canberra, ACT, AustraliaUC Research Institute for Sport and Exercise, University of Canberra, Canberra, ACT, AustraliaDiscipline of Sport and Exercise Science, Faculty of Health, University of Canberra, Canberra, ACT, AustraliaCentre for Research on Ageing, Health and Wellbeing, Australian National University, Canberra, ACT, AustraliaDiscipline of Sport and Exercise Science, Faculty of Health, University of Canberra, Canberra, ACT, AustraliaUC Research Institute for Sport and Exercise, University of Canberra, Canberra, ACT, AustraliaDiscipline of Sport and Exercise Science, Faculty of Health, University of Canberra, Canberra, ACT, AustraliaCentre for Research on Ageing, Health and Wellbeing, Australian National University, Canberra, ACT, AustraliaTurner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, VIC, AustraliaCentre for Research on Ageing, Health and Wellbeing, Australian National University, Canberra, ACT, AustraliaCentre for Research on Ageing, Health and Wellbeing, Australian National University, Canberra, ACT, AustraliaTurner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, VIC, AustraliaNeuroscience Research Australia, Randwick, NSW, AustraliaSchool of Psychology, University of New South Wales, Sydney, NSW, AustraliaHigh-intensity exercise has enhanced motor learning in healthy young adults. Anodal-transcranial direct current stimulation (a-tDCS) may optimize these effects. This study aimed to determine the effects of a short-term high-intensity interval exercise intervention either with or without a-tDCS on the learning and retention of a novel motor task in middle-aged adults. Forty-two healthy middle-aged adults (age = 44.6 ± 6.3, female = 76%) were randomized into three groups: exercise and active a-tDCS, exercise and sham a-tDCS, and a non-exercise and sham a-tDCS control. Participants completed a baseline testing session, followed by three intervention sessions 48-h apart. The exercise groups completed 20-min of high-intensity exercise followed by a novel sequential visual isometric pinch task (SVIPT) while receiving 20-min of 1.5 mA a-tDCS, or sham tDCS. The control group completed 20-min of reading before receiving sham a-tDCS during the SVIPT. Learning was assessed by skill change within and between intervention sessions. Participants returned 5–7 days after the final intervention session and performed the SVIPT task to assess retention. All three groups showed evidence of learning on the SVIPT task. Neither group displayed enhanced overall learning or retention when compared to the control group. High-intensity exercise with or without a-tDCS did not improve learning or retention of a novel motor task in middle-aged adults. The methodological framework provides direction for future research to investigate the potential of differing exercise intensity effects on learning and retention.https://www.frontiersin.org/articles/10.3389/fnhum.2021.661079/fullcognitionnon-invasive brain stimulationmotor cortexaerobic exercisetranscranial direct current stimulation |
| spellingShingle | Clare Quinlan Clare Quinlan Ben Rattray Ben Rattray Ben Rattray Disa Pryor Joseph M. Northey Joseph M. Northey Joseph M. Northey James Coxon Nicolas Cherbuin Sophie C. Andrews Sophie C. Andrews Sophie C. Andrews Sophie C. Andrews A Short-Term Intervention of High-Intensity Exercise and Anodal-tDCS on Motor Learning in Middle-Aged Adults: An RCT Frontiers in Human Neuroscience cognition non-invasive brain stimulation motor cortex aerobic exercise transcranial direct current stimulation |
| title | A Short-Term Intervention of High-Intensity Exercise and Anodal-tDCS on Motor Learning in Middle-Aged Adults: An RCT |
| title_full | A Short-Term Intervention of High-Intensity Exercise and Anodal-tDCS on Motor Learning in Middle-Aged Adults: An RCT |
| title_fullStr | A Short-Term Intervention of High-Intensity Exercise and Anodal-tDCS on Motor Learning in Middle-Aged Adults: An RCT |
| title_full_unstemmed | A Short-Term Intervention of High-Intensity Exercise and Anodal-tDCS on Motor Learning in Middle-Aged Adults: An RCT |
| title_short | A Short-Term Intervention of High-Intensity Exercise and Anodal-tDCS on Motor Learning in Middle-Aged Adults: An RCT |
| title_sort | short term intervention of high intensity exercise and anodal tdcs on motor learning in middle aged adults an rct |
| topic | cognition non-invasive brain stimulation motor cortex aerobic exercise transcranial direct current stimulation |
| url | https://www.frontiersin.org/articles/10.3389/fnhum.2021.661079/full |
| work_keys_str_mv | AT clarequinlan ashortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT clarequinlan ashortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT benrattray ashortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT benrattray ashortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT benrattray ashortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT disapryor ashortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT josephmnorthey ashortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT josephmnorthey ashortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT josephmnorthey ashortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT jamescoxon ashortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT nicolascherbuin ashortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT sophiecandrews ashortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT sophiecandrews ashortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT sophiecandrews ashortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT sophiecandrews ashortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT clarequinlan shortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT clarequinlan shortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT benrattray shortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT benrattray shortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT benrattray shortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT disapryor shortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT josephmnorthey shortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT josephmnorthey shortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT josephmnorthey shortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT jamescoxon shortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT nicolascherbuin shortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT sophiecandrews shortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT sophiecandrews shortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT sophiecandrews shortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct AT sophiecandrews shortterminterventionofhighintensityexerciseandanodaltdcsonmotorlearninginmiddleagedadultsanrct |