Intramedullary brachytherapy for the treatment of long bone metastatic disease: A case report

Abstract. Case:. A 56-year-old woman with metastatic melanoma and femoral lesions with impending pathologic fracture was indicated for intramedullary brachytherapy (IMBT) and intramedullary nail. Conclusions:. IMBT + intramedullary nail is a new technique for the treatment of long bone metastases. I...

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Main Authors: David Eric O'Neill, MD, Bhavani Gannavarapu, MD, Brian Hrycushko, PhD, Michael Folkert, MD, PhD, Robert Timmerman, MD, Alexandra Callan, MD
Format: Article
Language:English
Published: Wolters Kluwer 2023-06-01
Series:OTA International
Online Access:http://journals.lww.com/10.1097/OI9.0000000000000267
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author David Eric O'Neill, MD
Bhavani Gannavarapu, MD
Brian Hrycushko, PhD
Michael Folkert, MD, PhD
Robert Timmerman, MD
Alexandra Callan, MD
author_facet David Eric O'Neill, MD
Bhavani Gannavarapu, MD
Brian Hrycushko, PhD
Michael Folkert, MD, PhD
Robert Timmerman, MD
Alexandra Callan, MD
author_sort David Eric O'Neill, MD
collection DOAJ
description Abstract. Case:. A 56-year-old woman with metastatic melanoma and femoral lesions with impending pathologic fracture was indicated for intramedullary brachytherapy (IMBT) and intramedullary nail. Conclusions:. IMBT + intramedullary nail is a new technique for the treatment of long bone metastases. IMBT maximizes radiation to the tumor and minimizes radiation to surrounding tissues. It allows the patient to resume systemic treatment expediently. Our cadaver model and patient were both treated for femoral metastases; however, this technique allows for the treatment of any long bone. This is a safe technique that minimizes treatment time compared with other standard radiation regimens.
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spelling doaj.art-e2c30df5a85942318210e92509d5aa692023-09-28T07:17:33ZengWolters KluwerOTA International2574-21672023-06-0162e26710.1097/OI9.0000000000000267OI90000000000000267Intramedullary brachytherapy for the treatment of long bone metastatic disease: A case reportDavid Eric O'Neill, MD0Bhavani Gannavarapu, MD1Brian Hrycushko, PhD2Michael Folkert, MD, PhD3Robert Timmerman, MD4Alexandra Callan, MD5a Department of Orthopedic Surgery, UT Southwestern Medical Center, Dallas, TX; andb Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX.b Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX.b Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX.b Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX.a Department of Orthopedic Surgery, UT Southwestern Medical Center, Dallas, TX; andAbstract. Case:. A 56-year-old woman with metastatic melanoma and femoral lesions with impending pathologic fracture was indicated for intramedullary brachytherapy (IMBT) and intramedullary nail. Conclusions:. IMBT + intramedullary nail is a new technique for the treatment of long bone metastases. IMBT maximizes radiation to the tumor and minimizes radiation to surrounding tissues. It allows the patient to resume systemic treatment expediently. Our cadaver model and patient were both treated for femoral metastases; however, this technique allows for the treatment of any long bone. This is a safe technique that minimizes treatment time compared with other standard radiation regimens.http://journals.lww.com/10.1097/OI9.0000000000000267
spellingShingle David Eric O'Neill, MD
Bhavani Gannavarapu, MD
Brian Hrycushko, PhD
Michael Folkert, MD, PhD
Robert Timmerman, MD
Alexandra Callan, MD
Intramedullary brachytherapy for the treatment of long bone metastatic disease: A case report
OTA International
title Intramedullary brachytherapy for the treatment of long bone metastatic disease: A case report
title_full Intramedullary brachytherapy for the treatment of long bone metastatic disease: A case report
title_fullStr Intramedullary brachytherapy for the treatment of long bone metastatic disease: A case report
title_full_unstemmed Intramedullary brachytherapy for the treatment of long bone metastatic disease: A case report
title_short Intramedullary brachytherapy for the treatment of long bone metastatic disease: A case report
title_sort intramedullary brachytherapy for the treatment of long bone metastatic disease a case report
url http://journals.lww.com/10.1097/OI9.0000000000000267
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