Conceptual Design and Procedure for an Autonomous Intramyocardial Injection Catheter
This article discusses existing catheter systems and proposes a conceptual design and procedure for an autonomous cell injection catheter for the purpose of transferring committed myogenic or undifferentiated stem cells into the infarct boundary zones of the left ventricle. Operation of existing cat...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2017-05-01
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| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.3727/096368916X694256 |
| _version_ | 1818283842549579776 |
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| author | Weyland Cheng Peter K. Law |
| author_facet | Weyland Cheng Peter K. Law |
| author_sort | Weyland Cheng |
| collection | DOAJ |
| description | This article discusses existing catheter systems and proposes a conceptual design and procedure for an autonomous cell injection catheter for the purpose of transferring committed myogenic or undifferentiated stem cells into the infarct boundary zones of the left ventricle. Operation of existing catheters used for cell delivery is far from optimal. Commercial injection catheters available are handheld devices operated manually by means of tip deflection and torque capabilities. Interventionists require a hefty learning curve and often encounter difficulties in catheter stabilization and infarct detection, resulting in lengthy operation times and nonprecise injections. We examined current technologies and proposed a design incorporating robotic positional control, feedback signals, and an adaptable operational sequence to overcome these problems. The design provides the basis for robotic catheter construction that is able to autonomously assist the physician in transferring myogenic cells to the left ventricle infarct boundary zones. |
| first_indexed | 2024-12-13T00:43:20Z |
| format | Article |
| id | doaj.art-e2c37f74871546b780af001484677da1 |
| institution | Directory Open Access Journal |
| issn | 0963-6897 1555-3892 |
| language | English |
| last_indexed | 2024-12-13T00:43:20Z |
| publishDate | 2017-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Cell Transplantation |
| spelling | doaj.art-e2c37f74871546b780af001484677da12022-12-22T00:05:05ZengSAGE PublishingCell Transplantation0963-68971555-38922017-05-012610.3727/096368916X694256Conceptual Design and Procedure for an Autonomous Intramyocardial Injection CatheterWeyland Cheng0Peter K. Law1 Cell Therapy Institute, Wuhan, P.R. China Cell Therapy Institute, Wuhan, P.R. ChinaThis article discusses existing catheter systems and proposes a conceptual design and procedure for an autonomous cell injection catheter for the purpose of transferring committed myogenic or undifferentiated stem cells into the infarct boundary zones of the left ventricle. Operation of existing catheters used for cell delivery is far from optimal. Commercial injection catheters available are handheld devices operated manually by means of tip deflection and torque capabilities. Interventionists require a hefty learning curve and often encounter difficulties in catheter stabilization and infarct detection, resulting in lengthy operation times and nonprecise injections. We examined current technologies and proposed a design incorporating robotic positional control, feedback signals, and an adaptable operational sequence to overcome these problems. The design provides the basis for robotic catheter construction that is able to autonomously assist the physician in transferring myogenic cells to the left ventricle infarct boundary zones.https://doi.org/10.3727/096368916X694256 |
| spellingShingle | Weyland Cheng Peter K. Law Conceptual Design and Procedure for an Autonomous Intramyocardial Injection Catheter Cell Transplantation |
| title | Conceptual Design and Procedure for an Autonomous Intramyocardial Injection Catheter |
| title_full | Conceptual Design and Procedure for an Autonomous Intramyocardial Injection Catheter |
| title_fullStr | Conceptual Design and Procedure for an Autonomous Intramyocardial Injection Catheter |
| title_full_unstemmed | Conceptual Design and Procedure for an Autonomous Intramyocardial Injection Catheter |
| title_short | Conceptual Design and Procedure for an Autonomous Intramyocardial Injection Catheter |
| title_sort | conceptual design and procedure for an autonomous intramyocardial injection catheter |
| url | https://doi.org/10.3727/096368916X694256 |
| work_keys_str_mv | AT weylandcheng conceptualdesignandprocedureforanautonomousintramyocardialinjectioncatheter AT peterklaw conceptualdesignandprocedureforanautonomousintramyocardialinjectioncatheter |