Associations of Habitual Mineral Intake with New-Onset Prediabetes/Diabetes after Acute Pancreatitis
Associations between habitual dietary intake of minerals and glucose metabolism have been extensively studied in relation to metabolic disorders. However, similar research has yet to be conducted in individuals after acute pancreatitis (AP). The main aim was to investigate the associations between h...
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MDPI AG
2021-11-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/13/11/3978 |
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| author | Claire F. Norbitt Wandia Kimita Juyeon Ko Sakina H. Bharmal Maxim S. Petrov |
| author_facet | Claire F. Norbitt Wandia Kimita Juyeon Ko Sakina H. Bharmal Maxim S. Petrov |
| author_sort | Claire F. Norbitt |
| collection | DOAJ |
| description | Associations between habitual dietary intake of minerals and glucose metabolism have been extensively studied in relation to metabolic disorders. However, similar research has yet to be conducted in individuals after acute pancreatitis (AP). The main aim was to investigate the associations between habitual intake of 13 minerals and glycaemic status: new-onset prediabetes/diabetes after AP (NODAP), pre-existing prediabetes/type 2 diabetes (T2DM), and normoglycaemia after AP (NAP). Associations between the dietary intake of minerals and markers of glucose metabolism (glycated haemoglobin and fasting plasma glucose) were also studied. The EPIC-Norfolk food frequency questionnaire was used in a cross-sectional fashion to determine the habitual intake of 13 dietary minerals. ANCOVA as well as multiple linear regression analyses were conducted and five statistical models were built to adjust for covariates. The study included 106 individuals after AP. In the NODAP group, intake of 4 minerals was significantly less when compared with the NAP group: iron (B = −0.076, <i>p</i> = 0.013), nitrogen (B = −0.066, <i>p</i> = 0.003), phosphorous (B = −0.046, <i>p</i> = 0.006), and zinc (B = −0.078, <i>p</i> = 0.001). Glycated haemoglobin was significantly associated with iodine intake (B = 17.763, <i>p</i> = 0.032) and manganese intake (B = −17.147, <i>p</i> = 0.003) in the NODAP group. Fasting plasma glucose was significantly associated with manganese intake (B = −2.436, <i>p</i> = 0.027) in the NODAP group. Habitual intake of minerals differs between individuals with NODAP, T2DM, and NAP. Prospective longitudinal studies and randomised controlled trials are now warranted to further investigate the associations between mineral intake and NODAP. |
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| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T05:11:23Z |
| publishDate | 2021-11-01 |
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| series | Nutrients |
| spelling | doaj.art-e2c512886e2f4525a6f8262be60561e92023-11-23T00:48:49ZengMDPI AGNutrients2072-66432021-11-011311397810.3390/nu13113978Associations of Habitual Mineral Intake with New-Onset Prediabetes/Diabetes after Acute PancreatitisClaire F. Norbitt0Wandia Kimita1Juyeon Ko2Sakina H. Bharmal3Maxim S. Petrov4School of Medicine, University of Auckland, Auckland 1023, New ZealandSchool of Medicine, University of Auckland, Auckland 1023, New ZealandSchool of Medicine, University of Auckland, Auckland 1023, New ZealandSchool of Medicine, University of Auckland, Auckland 1023, New ZealandSchool of Medicine, University of Auckland, Auckland 1023, New ZealandAssociations between habitual dietary intake of minerals and glucose metabolism have been extensively studied in relation to metabolic disorders. However, similar research has yet to be conducted in individuals after acute pancreatitis (AP). The main aim was to investigate the associations between habitual intake of 13 minerals and glycaemic status: new-onset prediabetes/diabetes after AP (NODAP), pre-existing prediabetes/type 2 diabetes (T2DM), and normoglycaemia after AP (NAP). Associations between the dietary intake of minerals and markers of glucose metabolism (glycated haemoglobin and fasting plasma glucose) were also studied. The EPIC-Norfolk food frequency questionnaire was used in a cross-sectional fashion to determine the habitual intake of 13 dietary minerals. ANCOVA as well as multiple linear regression analyses were conducted and five statistical models were built to adjust for covariates. The study included 106 individuals after AP. In the NODAP group, intake of 4 minerals was significantly less when compared with the NAP group: iron (B = −0.076, <i>p</i> = 0.013), nitrogen (B = −0.066, <i>p</i> = 0.003), phosphorous (B = −0.046, <i>p</i> = 0.006), and zinc (B = −0.078, <i>p</i> = 0.001). Glycated haemoglobin was significantly associated with iodine intake (B = 17.763, <i>p</i> = 0.032) and manganese intake (B = −17.147, <i>p</i> = 0.003) in the NODAP group. Fasting plasma glucose was significantly associated with manganese intake (B = −2.436, <i>p</i> = 0.027) in the NODAP group. Habitual intake of minerals differs between individuals with NODAP, T2DM, and NAP. Prospective longitudinal studies and randomised controlled trials are now warranted to further investigate the associations between mineral intake and NODAP.https://www.mdpi.com/2072-6643/13/11/3978manganeseironiodineseleniumhabitual mineral intakepancreatitis |
| spellingShingle | Claire F. Norbitt Wandia Kimita Juyeon Ko Sakina H. Bharmal Maxim S. Petrov Associations of Habitual Mineral Intake with New-Onset Prediabetes/Diabetes after Acute Pancreatitis Nutrients manganese iron iodine selenium habitual mineral intake pancreatitis |
| title | Associations of Habitual Mineral Intake with New-Onset Prediabetes/Diabetes after Acute Pancreatitis |
| title_full | Associations of Habitual Mineral Intake with New-Onset Prediabetes/Diabetes after Acute Pancreatitis |
| title_fullStr | Associations of Habitual Mineral Intake with New-Onset Prediabetes/Diabetes after Acute Pancreatitis |
| title_full_unstemmed | Associations of Habitual Mineral Intake with New-Onset Prediabetes/Diabetes after Acute Pancreatitis |
| title_short | Associations of Habitual Mineral Intake with New-Onset Prediabetes/Diabetes after Acute Pancreatitis |
| title_sort | associations of habitual mineral intake with new onset prediabetes diabetes after acute pancreatitis |
| topic | manganese iron iodine selenium habitual mineral intake pancreatitis |
| url | https://www.mdpi.com/2072-6643/13/11/3978 |
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