Unraveling the link: environmental tobacco smoke exposure and its impact on infertility among American women (18–50 years)
PurposeThe detrimental effects of environmental tobacco smoke (ETS) on women’s reproductive health have been widely recognized. However, the detailed association between exposure to environmental tobacco smoke and the incidence of infertility remains under-explored. This investigation focuses on exp...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-03-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1358290/full |
| _version_ | 1797269076318355456 |
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| author | Liang Peng Xiaohan Luo Baodi Cao Xiaohui Wang |
| author_facet | Liang Peng Xiaohan Luo Baodi Cao Xiaohui Wang |
| author_sort | Liang Peng |
| collection | DOAJ |
| description | PurposeThe detrimental effects of environmental tobacco smoke (ETS) on women’s reproductive health have been widely recognized. However, the detailed association between exposure to environmental tobacco smoke and the incidence of infertility remains under-explored. This investigation focuses on exploring this potential connection.MethodsFor this analysis, we extracted data from the US National Health and Nutrition Examination Survey (NHANES) database, covering the years 2013 to 2018, focusing on individuals with recorded serum cotinine levels and infertility information. ETS exposure and fertility status were analyzed as independent and dependent variables, respectively. We applied weighted multivariate logistic regression method to evaluate the impact of ETS on infertility, including subgroup analyses for more detailed insights.ResultsThe study encompassed 3,343 participants. Logistic regression analysis revealed a notable positive correlation between ETS exposure and infertility, with an odds ratio (OR) of 1.64 (95% Confidence Interval [CI]: 1.14–2.36). We observed a non-linear relationship between ETS exposure and infertility risk. Notably, infertility risk increased by 64% in serum cotinine levels above 0.136 compared to that in serum cotinine levels below 0.011. Further, subgroup analysis and interaction tests showed consistent results across different segments, underscoring the robustness of the ETS-infertility link.ConclusionOur findings suggest that environmental tobacco smoke exposure may be a contributing factor to infertility. These results reinforce the recommendation for women in their reproductive years to avoid ETS exposure, especially when planning for pregnancy. |
| first_indexed | 2024-04-25T01:42:37Z |
| format | Article |
| id | doaj.art-e2c692b6646143749566b24b971c04c6 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-04-25T01:42:37Z |
| publishDate | 2024-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-e2c692b6646143749566b24b971c04c62024-03-08T04:44:50ZengFrontiers Media S.A.Frontiers in Public Health2296-25652024-03-011210.3389/fpubh.2024.13582901358290Unraveling the link: environmental tobacco smoke exposure and its impact on infertility among American women (18–50 years)Liang PengXiaohan LuoBaodi CaoXiaohui WangPurposeThe detrimental effects of environmental tobacco smoke (ETS) on women’s reproductive health have been widely recognized. However, the detailed association between exposure to environmental tobacco smoke and the incidence of infertility remains under-explored. This investigation focuses on exploring this potential connection.MethodsFor this analysis, we extracted data from the US National Health and Nutrition Examination Survey (NHANES) database, covering the years 2013 to 2018, focusing on individuals with recorded serum cotinine levels and infertility information. ETS exposure and fertility status were analyzed as independent and dependent variables, respectively. We applied weighted multivariate logistic regression method to evaluate the impact of ETS on infertility, including subgroup analyses for more detailed insights.ResultsThe study encompassed 3,343 participants. Logistic regression analysis revealed a notable positive correlation between ETS exposure and infertility, with an odds ratio (OR) of 1.64 (95% Confidence Interval [CI]: 1.14–2.36). We observed a non-linear relationship between ETS exposure and infertility risk. Notably, infertility risk increased by 64% in serum cotinine levels above 0.136 compared to that in serum cotinine levels below 0.011. Further, subgroup analysis and interaction tests showed consistent results across different segments, underscoring the robustness of the ETS-infertility link.ConclusionOur findings suggest that environmental tobacco smoke exposure may be a contributing factor to infertility. These results reinforce the recommendation for women in their reproductive years to avoid ETS exposure, especially when planning for pregnancy.https://www.frontiersin.org/articles/10.3389/fpubh.2024.1358290/fullenvironmental tobacco smokeinfertilityserum cotininenon-linearityNHANES |
| spellingShingle | Liang Peng Xiaohan Luo Baodi Cao Xiaohui Wang Unraveling the link: environmental tobacco smoke exposure and its impact on infertility among American women (18–50 years) Frontiers in Public Health environmental tobacco smoke infertility serum cotinine non-linearity NHANES |
| title | Unraveling the link: environmental tobacco smoke exposure and its impact on infertility among American women (18–50 years) |
| title_full | Unraveling the link: environmental tobacco smoke exposure and its impact on infertility among American women (18–50 years) |
| title_fullStr | Unraveling the link: environmental tobacco smoke exposure and its impact on infertility among American women (18–50 years) |
| title_full_unstemmed | Unraveling the link: environmental tobacco smoke exposure and its impact on infertility among American women (18–50 years) |
| title_short | Unraveling the link: environmental tobacco smoke exposure and its impact on infertility among American women (18–50 years) |
| title_sort | unraveling the link environmental tobacco smoke exposure and its impact on infertility among american women 18 50 years |
| topic | environmental tobacco smoke infertility serum cotinine non-linearity NHANES |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1358290/full |
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