RelA-Induced Interferon Response Negatively Regulates Proliferation.

RelA-Induced Interferon Response Negatively Regulates Proliferation.

Both oncogenic and tumor-suppressor activities are attributed to the Nuclear Factor kappa B (NF-kB) pathway. Moreover, NF-kB may positively or negatively regulate proliferation. The molecular determinants of these opposing roles of NF-kB are unclear. Using primary human mammary epithelial cells (HME...

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Main Authors: Bose S Kochupurakkal, Zhigang C Wang, Tony Hua, Aedin C Culhane, Scott J Rodig, Koraljka Rajkovic-Molek, Jean-Bernard Lazaro, Andrea L Richardson, Debajit K Biswas, J Dirk Iglehart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4604146?pdf=render

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