A concise and scalable chemoenzymatic synthesis of prostaglandins

Abstract Prostaglandins have garnered significant attention from synthetic chemists due to their exceptional biological activities. In this report, we present a concise chemoenzymatic synthesis method for several representative prostaglandins, achieved in 5 to 7 steps. Notably, the common intermedia...

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Bibliographic Details
Main Authors: Yunpeng Yin, Jinxin Wang, Jian Li
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46960-y