Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome

There is no well-established procedure for the management of small penis syndrome (SPS), especially when psychological interventions fail. This study aimed at systematically evaluating the physical and psychological benefits of penile augmentation (PA) using injectable hyaluronic acid (HA) gel. Thir...

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Main Authors: Chun-Long Zhang, Yuan Quan, He Li, Qing Li, Wen-Jun Bai, Tao Xu, Xiao-Wei Zhang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Asian Journal of Andrology
Subjects:
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2022;volume=24;issue=6;spage=601;epage=606;aulast=Zhang
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author Chun-Long Zhang
Yuan Quan
He Li
Qing Li
Wen-Jun Bai
Tao Xu
Xiao-Wei Zhang
author_facet Chun-Long Zhang
Yuan Quan
He Li
Qing Li
Wen-Jun Bai
Tao Xu
Xiao-Wei Zhang
author_sort Chun-Long Zhang
collection DOAJ
description There is no well-established procedure for the management of small penis syndrome (SPS), especially when psychological interventions fail. This study aimed at systematically evaluating the physical and psychological benefits of penile augmentation (PA) using injectable hyaluronic acid (HA) gel. Thirty-eight patients receiving PA with HA gel from January 2017 to March 2020 were included and followed up for 1 year. Penile size, erectile function, and psychological burden measured by the Index of Male Genital Image (IMGI), Index of International Erectile Function (IIEF), and Beliefs about Penis Size (BPAS), respectively, were assessed at the beginning and at 1, 3, 6, and 12 months postinjection. The volume of HA gel injected was 21.5 ± 3.7 ml. Compared to baseline data, flaccid penile girth and length significantly increased by 3.41 ± 0.95 cm (P < 0.01) and 2.55 ± 0.55 cm (P < 0.01) at the 1st month postinjection, respectively. At the endpoint, despite attenuations, statistically significant improvements in flaccid penis size were still obtained, namely 2.44 ± 1.14 cm in girth (P < 0.01) and 1.65 ± 0.59 cm in length (P < 0.01). Similarly, erectile penile girth statistically increased by 1.32 ± 1.02 cm (P < 0.01) at the 1st month but were only 0.80 ± 0.54 cm bigger than baseline (P < 0.01) at the endpoint. At the 1st month, the average score of IMGI and the mean score of IIEF statistically increased by 46.2 ± 10.5 (P < 0.01) and 7.6 ± 6.2 (P < 0.01), respectively; the score of BAPS significantly decreased by 18.3 ± 4.5 (P < 0.01). These alterations remained steady during follow-up. Considering the significant penile size improvement, lasting psychological benefit, and low complication rate, PA with HA might serve as an appropriate alternative for patients with SPS.
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spelling doaj.art-e2ceb30d366c427d988e1b0041c1052a2022-12-22T03:41:34ZengWolters Kluwer Medknow PublicationsAsian Journal of Andrology1008-682X1745-72622022-01-0124660160610.4103/aja20223Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndromeChun-Long ZhangYuan QuanHe LiQing LiWen-Jun BaiTao XuXiao-Wei ZhangThere is no well-established procedure for the management of small penis syndrome (SPS), especially when psychological interventions fail. This study aimed at systematically evaluating the physical and psychological benefits of penile augmentation (PA) using injectable hyaluronic acid (HA) gel. Thirty-eight patients receiving PA with HA gel from January 2017 to March 2020 were included and followed up for 1 year. Penile size, erectile function, and psychological burden measured by the Index of Male Genital Image (IMGI), Index of International Erectile Function (IIEF), and Beliefs about Penis Size (BPAS), respectively, were assessed at the beginning and at 1, 3, 6, and 12 months postinjection. The volume of HA gel injected was 21.5 ± 3.7 ml. Compared to baseline data, flaccid penile girth and length significantly increased by 3.41 ± 0.95 cm (P < 0.01) and 2.55 ± 0.55 cm (P < 0.01) at the 1st month postinjection, respectively. At the endpoint, despite attenuations, statistically significant improvements in flaccid penis size were still obtained, namely 2.44 ± 1.14 cm in girth (P < 0.01) and 1.65 ± 0.59 cm in length (P < 0.01). Similarly, erectile penile girth statistically increased by 1.32 ± 1.02 cm (P < 0.01) at the 1st month but were only 0.80 ± 0.54 cm bigger than baseline (P < 0.01) at the endpoint. At the 1st month, the average score of IMGI and the mean score of IIEF statistically increased by 46.2 ± 10.5 (P < 0.01) and 7.6 ± 6.2 (P < 0.01), respectively; the score of BAPS significantly decreased by 18.3 ± 4.5 (P < 0.01). These alterations remained steady during follow-up. Considering the significant penile size improvement, lasting psychological benefit, and low complication rate, PA with HA might serve as an appropriate alternative for patients with SPS.http://www.ajandrology.com/article.asp?issn=1008-682X;year=2022;volume=24;issue=6;spage=601;epage=606;aulast=Zhanghyaluronic acid; penile augmentation; small penis syndrome
spellingShingle Chun-Long Zhang
Yuan Quan
He Li
Qing Li
Wen-Jun Bai
Tao Xu
Xiao-Wei Zhang
Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome
Asian Journal of Andrology
hyaluronic acid; penile augmentation; small penis syndrome
title Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome
title_full Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome
title_fullStr Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome
title_full_unstemmed Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome
title_short Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome
title_sort penile augmentation with injectable hyaluronic acid gel an alternative choice for small penis syndrome
topic hyaluronic acid; penile augmentation; small penis syndrome
url http://www.ajandrology.com/article.asp?issn=1008-682X;year=2022;volume=24;issue=6;spage=601;epage=606;aulast=Zhang
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