Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses
Summary: Human bone marrow (BM) plasma cells are heterogeneous, ranging from newly arrived antibody-secreting cells (ASCs) to long-lived plasma cells (LLPCs). We provide single-cell transcriptional resolution of 17,347 BM ASCs from five healthy adults. Fifteen clusters are identified ranging from ne...
Main Authors: | Meixue Duan, Doan C. Nguyen, Chester J. Joyner, Celia L. Saney, Christopher M. Tipton, Joel Andrews, Sagar Lonial, Caroline Kim, Ian Hentenaar, Astrid Kosters, Eliver Ghosn, Annette Jackson, Stuart Knechtle, Stalinraja Maruthamuthu, Sindhu Chandran, Tom Martin, Raja Rajalingam, Flavio Vincenti, Cynthia Breeden, Ignacio Sanz, Greg Gibson, F. Eun-Hyung Lee |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-07-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124723006939 |
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