Nanoparticles Based on Quaternary Ammonium Chitosan-methyl-β-cyclodextrin Conjugate for the Neuropeptide Dalargin Delivery to the Central Nervous System: An In Vitro Study
Peptide oral administration is a hard goal to reach, especially if the brain is the target site. The purpose of the present study was to set up a vehicle apt to promote oral absorption of the neuropeptide dalargin (DAL), allowing it to cross the intestinal mucosal barrier, resist enzymatic degradati...
Main Authors: | Chiara Migone, Letizia Mattii, Martina Giannasi, Stefania Moscato, Andrea Cesari, Ylenia Zambito, Anna Maria Piras |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-12-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/13/1/5 |
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